Comparison of the effects of different doses of acepromazine-xylazine on the electrocardiogram in dogs | ||
Iranian Journal of Veterinary Research | ||
مقاله 1، دوره 10، شماره 3 - شماره پیاپی 28، 2009، صفحه 208-215 اصل مقاله (111.51 K) | ||
نوع مقاله: Full paper (Original article) | ||
شناسه دیجیتال (DOI): 10.22099/ijvr.2009.1694 | ||
نویسندگان | ||
A. A. Sarchahi* 1؛ N. Vesal1؛ B. Nikahval2؛ A. Karampour3 | ||
1Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
2Ph.D. Student in Surgery, Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
3Graduated from School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
چکیده | ||
Seventy seven adult large mixed breed dogs of either sex were included in this study. The animals were randomly divided into four groups and received the following drug combinations intramuscularly: Group 1 xylazine (0.5 mg/kg) and acepromazine (0.05 mg/kg), Group 2 xylazine (0.8 mg/kg) and acepromazine (0.03 mg/kg), Group 3 xylazine (0.3 mg/kg) and acepromazine (0.08 mg/kg) and Group 4 xylazine (0.5 mg/kg) acepromazine (0.05 mg/kg) and atropine (0.04 mg/kg). Results showed no significant differences in the Pwave and QRS complex durations, PR interval and R waves among the 4 groups. QT interval significantly decreased following drug administration in group 4 compared to groups 1 (P = 0.03) and 3 (P = 0.004). There were significant increases in the QT interval in groups 1 (P = 0.001) and 3 (P = 0.01) after drug injections. Heart rate (HR) significantly decreased in groups 1, 2 and 3 after drug injections (P = 0.004, 0.01 and 0.03, respectively). There was a significant negative correlation between HR, PR and QT intervals, and a positive correlation between HR and P-wave amplitude. There were no significant differences between all groups in the incidence of first and second degree AV blocks. | ||
کلیدواژهها | ||
Acepromazine؛ Atropine؛ dog؛ Electrocardiogram؛ Xylazine | ||
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