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Penile hemangiosarcoma as a cause of stranguria in a dog: clinical presentation, imaging findings, treatment and out-come | ||
| Iranian Journal of Veterinary Research | ||
| دوره 25، شماره 1 - شماره پیاپی 86، 2024، صفحه 74-78 اصل مقاله (1.07 M) | ||
| نوع مقاله: Scientific report | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2024.48685.7113 | ||
| نویسندگان | ||
| A. Pierini* 1؛ C. Picchi1؛ G. Pisani1؛ D. Binanti2؛ A. Carli1؛ F. Rossi3؛ M. C. Criscuolo1 | ||
| 1Centro Veterinario Pisani-Carli-Chiodo Animalia, via Togliatti 8, 19034 Luni, SP, Italy | ||
| 2AbLab, Laboratorio di Analisi Veterinarie, via privata Massa Neri, 19038 Sarzana, SP, Italy | ||
| 3AniCura Clinica Veterinaria dell’Orologio, Via A. Gramsci, 1/5, 40037 Sasso Marconi, BO, Italy | ||
| چکیده | ||
| Background: Penile tumors are rare in dogs and only single case reports or small case series have been reported. Case description: An 11-year-old, cross-breed dog was presented for a two-week history of stranguria. At physical examination, a subcutaneous swelling of the penis was detected. Abdominal radiographs, ultrasonography, and CT showed a subcutaneous penile mass involving the penile urethra and bulbus glandis associated with marked lysis of the os penis. Histological features along with the neoplastic cell positivity to CD31 and FVIII immunohistochemical markers warranted a final diagnosis of penile hemangiosarcoma. Findings/treatment and outcome: The dog was treated with amputation of the penis, scrotal urethrostomy, and five adjuvant doses of doxorubicin along with thalidomide. Cutaneous and omental metastases were found 235 days after surgery. The dog was euthanized at 296 days due to bone and pulmonary metastasis. Conclusion: Penile hemangiosarcoma seems to share the same aggressive behavior with other hemangiosarcomas seen in other anatomical locations. Therefore, surgery and chemotherapy may improve survival time in dogs with penile hemangiosarcoma as well. | ||
| کلیدواژهها | ||
| Doxorubicin؛ Neoplasm؛ Thalidomide | ||
| مراجع | ||
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Bolfer, L; Schmit, JM; MacNeill, AL; Ragetly, CA; Bennett, RA and McMichael, M (2015). Penile amputation and scrotal urethrostomy followed by chemotherapy in a dog with penile hemangiosarcoma. J. Am. Anim. Hosp. Assoc., 51: 25-30.
Bray, JP; Orbell, G; Cave, N and Munday, JS (2018). Does thalidomide prolong survival in dogs with splenic haemangiosarcoma? J. Small Anim. Pract., 59: 85-91.
Bulakowski, EJ; Philibert, JC; Siegel, S; Clifford, CA; Ribson, R; Zivin, K and Cronin, KL (2008). Intramuscular hemangiosarcoma. J. Am. Vet. Med. Assoc., 233: 122-128.
Burchell, RK; Kirberger, RM and Janse van Rensburg, DD (2014). Haemangiosarcoma of the os penis in a dog: The most common neoplasm of the canine penis. J. S. Afr. Vet. Assoc., 85: 1-4. Burrow, RD; Gregory, SP; Giejda, AA and White, RN (2011). Penile amputation and scrotal urethrostomy in 18 dogs. Vet. Rec., 169: 657.
Fry, JK; Burney, D; Hottinger, H; Fabiani, M and Feagin, C (2014). Pollakiuria and stranguria in a labrador retriever with penile HSA. J. Am. Anim. Hosp. Assoc., 50: 141-147.
Giuffrida, MA; Kamstock, DA; Selmic, LE; Pass, W; Szivek, A; Mison, MB; Boston, SE; Fox, LE; Robat, C; Grimes, JA; Maritato, KC and Bacon, NJ (2018). Primary appendicular hemangiosarcoma and telangiectatic osteosarcoma in 70 dogs: A Veterinary Society of Surgical Oncology retrospective study. Vet. Surg., 47: 774-783.
Griffin, MA; Culp, WTN and Rebhun, RB (2021). Canine and feline haemangiosarcoma. Vet. Rec., 189: e585.
LeBlanc, AK; Atherton, M; Bentley, RT; Boudreau, CE; Burton, JH; Curran, KM; Dow, S; Giuffrida, MA; Kellihan, HB; Mason, NJ; Oblak, M; Selmic, LE; Selting, KA; Singh, A; Vail, DM; Weishaar, KM; Berger, EP; Rossmeisl, JH and Mazcko, C (2021). Veterinary Cooperative Oncology Group common terminology criteria for adverse events (VCOG-CTCAE v2) following investigational therapy in dogs and cats. Vet. Comp. Oncol., 19: 311-352.
Marolf, A; Specht, A; Thompson, M and Castleman, W (2006). Imaging diagnosis: Penile hemangiosarcoma. Vet. Radiol. Ultrasound., 47: 474-475.
Mellanby, RJ; Chantrey, JC; Baines, EA; Ailsby, RL and Herrtage, ME (2004). Urethral haemangiosarcoma in a boxer. J. Small Anim. Pract., 45: 154-156.
Mullin, C and Clifford, CA (2020). Miscellaneous tumors. In: Vail, DM; Thamm, DH and Liptak, JM (Eds.), Withrow & MacEwen’s small animal clinical oncology. (6th Edn.), Elsevier, Riverport Lane, St. Luis, Missuri. PP: 645-656.
Nguyen, SM; Thamm, DH and Vail, DM (2015). Response evaluation criteria for solid tumours in dogs (v1.0): A Veterinary Cooperative Oncology Group (VCOG) consensus document. Vet. Comp. Oncol., 13: 176-183.
Pierini, A; Sartini, I; Giorgi, M; Łebkowska-Wieruszewska, B; Lisowski, S; Poapolathep, A and Marchetti, V (2020). Pharmacokinetics of thalidomide in dogs: can feeding affect it? A preliminary study. J. Vet. Sci., 21: 1-11.
Radhakrishnan, A (2017). Urethral stenting for obstructive uropathy utilizing digital radiography for guidance: Feasibility and clinical outcome in 26 dogs. J. Vet. Intern. Med., 31: 427-433.
Shiu, KB; Flory, AB; Anderson, CL; Wypij, J; Saba, C; Wilson, H; Kurzman, I and Chun, R (2011). Predictors of outcome in dogs with subcutaneous or intramuscular hemangiosarcoma. J. Am. Vet. Med. Assoc., 238: 472-479. | ||
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