اخبار و اعلانات

 آمار

تعداد نشریات24
تعداد شماره‌ها862
تعداد مقالات7,672
تعداد مشاهده مقاله13,668,611
تعداد دریافت فایل اصل مقاله11,743,147
Smiline Girija, S. A.. (1403). Hijacking the epigenetic mechanisms of A. baumannii. , 13(2), 51-53. doi: 10.22099/mbrc.2024.48801.1899
S. A. Smiline Girija. "Hijacking the epigenetic mechanisms of A. baumannii". , 13, 2, 1403, 51-53. doi: 10.22099/mbrc.2024.48801.1899
Smiline Girija, S. A.. (1403). 'Hijacking the epigenetic mechanisms of A. baumannii', , 13(2), pp. 51-53. doi: 10.22099/mbrc.2024.48801.1899
Smiline Girija, S. A.. Hijacking the epigenetic mechanisms of A. baumannii. , 1403; 13(2): 51-53. doi: 10.22099/mbrc.2024.48801.1899

Hijacking the epigenetic mechanisms of A. baumannii

Molecular Biology Research Communications
دوره 13، شماره 2، 2024، صفحه 51-53    اصل مقاله (101.05 K)
نوع مقاله: Invited review article
شناسه دیجیتال (DOI): 10.22099/mbrc.2024.48801.1899
نویسنده
S. A. Smiline Girija*
Department of Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-600 077, Tamilnadu, India
چکیده
Epigenetic mechanisms attribute to the resistance and virulence of Acinetobacter baumannii sparking a renewed area of research. Unveiling the targets pertained to the epigenetic modulation in the bacterium would aid in the curbing its complications in various recalcitrant infections. This review thus throws light on the various epigenetic mechanisms exhibited by A. bauamnnii, urging the need to implement epigenetic based novel strategies in precision medicine.
کلیدواژه‌ها
Epigenetics؛ Methylation؛ Acetylation؛ A. baumannii؛ Virulence؛ Epidrugs
مراجع
  1. Natalie Silmon C, Kami Kim. Pathogens Hijack the epigenome. A new twist on host-pathogen interactions. Am J Pathol 2014;184:897-911.
  2. Liao JH, Tsai CH, Patel SG, Yang JT, Tu IF, Lo Cicero M, Lipka-Lloyd M, Wu WL, Shen WJ, Ho MR, Chou CC, Sharma Gr, Okanishi H, Luk LYP, Tsai YH, Wu SH. Acetylome of Acinetobacter baumannii SK17 reveals a highly-conserved modification of histone-like protein HU. Front Mol Biosci 2017;4:77.
  3. Moon DC, Choi CH, Lee SM, Lee JH, Kim SI, Lee JC. Nuclear translocation of Acinetobacter baumannii transposase induces DNA methylation of CpG regions in the promoters of E-cadherin gene. PLoS One 2012;7:e38974.
  4. Crua Asensio N, Macho Rendón J, Torrent Burgas M. Time-resolved transcriptional profiling of epithelial cells infected by intracellular Acinetobacter baumannii. Microorganisms 2021;9:354.
  5. Ulrike Blaschkea , Beneditta Suwonoa , Sachli Zafarib , Ebersberger I, Skiebe E, Jeffries CM, Svergun DI, Wilharm G. Recombinant production of A1S_0222 from Acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity. Protein Expr Purif 2018;151:78-85.
  6. Fernandes JC, Acuña SM, Aoki JI, Floeter-Winter LM, Muxel SM. Long Non-Coding RNAs in the regulation of gene expression: physiology and disease. Noncoding RNA 2019;5:17.
  7. An Z, Ding W. Acinetobacter baumannii up-regulates LncRNA-GAS5 and promotes the degradation of STX17 by blocking the activation of YY1. Virulence 2021;12: 1965-1979.
آمار
تعداد مشاهده مقاله: 700
تعداد دریافت فایل اصل مقاله: 520


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب