اخبار و اعلانات

ارتقای جایگاه علمی نشریات دانشگاه شیراز در رتبه‌بندی‌های بین‌المللی و منطقه‌ای
به مناسبت هفته پژوهش و فناوری، مرکز نشر دانشگاه شیراز برگزار می‌کند: معرفی کتاب: مشاوره، توانبخشی و آموزش دانش‌آموزان با نیازهای ویژه و خانواده‌ آنان
به مناسبت هفته پژوهش و فناوری، مرکز نشر دانشگاه شیراز برگزار می‌کند: معرفی کتاب دو رساله در حالات و کرامات حضرت شاهچراغ (ع)
برگزاری کارگاه اصول انتشار کتاب در ناشران بین‌المللی
ارتقاء رتبه دو نشریه علمی دانشگاه شیراز در ارزیابی سامانه رتبه‌بندی نشریات کشور
فیلم دوره آموزشی هوش مصنوعی: SWOT و سیاست‌های ناشران بین‌المللی
ارتقاء رتبه نشریه علمی «شعرپژوهی» دانشگاه شیراز در ارزیابی سامانه رتبه‌بندی نشریات کشور
افتخارآفرینی دبیران مجلات علمی دانشگاه شیراز در عرصۀ بین‌المللی
اطلاعیه برگزاری دوره آموزشی هوش مصنوعی: SWOT و سیاست‌های ناشران بین‌المللی در تاریخ 19 خرداد 1404
ارتقاء رتبۀ مجلۀ علوم ایران از Q3 به Q2

 آمار

تعداد نشریات24
تعداد شماره‌ها907
تعداد مقالات8,106
تعداد مشاهده مقاله15,505,987
تعداد دریافت فایل اصل مقاله13,153,775
Vettri Saravanan, Rakshitha, Pandi, Anitha, Murthykumar, Karthikeyan, Girija Aseervatham Selvi, Smiline, Arumugam, Paramasivam, Priyadharsini Jayaseelan, Vijayashree. (1402). Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study. , 12(4), 133-137. doi: 10.22099/mbrc.2023.46999.1815
Rakshitha Vettri Saravanan; Anitha Pandi; Karthikeyan Murthykumar; Smiline Girija Aseervatham Selvi; Paramasivam Arumugam; Vijayashree Priyadharsini Jayaseelan. "Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study". , 12, 4, 1402, 133-137. doi: 10.22099/mbrc.2023.46999.1815
Vettri Saravanan, Rakshitha, Pandi, Anitha, Murthykumar, Karthikeyan, Girija Aseervatham Selvi, Smiline, Arumugam, Paramasivam, Priyadharsini Jayaseelan, Vijayashree. (1402). 'Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study', , 12(4), pp. 133-137. doi: 10.22099/mbrc.2023.46999.1815
Vettri Saravanan, Rakshitha, Pandi, Anitha, Murthykumar, Karthikeyan, Girija Aseervatham Selvi, Smiline, Arumugam, Paramasivam, Priyadharsini Jayaseelan, Vijayashree. Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study. , 1402; 12(4): 133-137. doi: 10.22099/mbrc.2023.46999.1815

Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study

Molecular Biology Research Communications
دوره 12، شماره 4، 2023، صفحه 133-137    اصل مقاله (131.95 K)
نوع مقاله: Original article
شناسه دیجیتال (DOI): 10.22099/mbrc.2023.46999.1815
نویسندگان
Rakshitha Vettri Saravanan1؛ Anitha Pandi2؛ Karthikeyan Murthykumar3؛ Smiline Girija Aseervatham Selvi1؛ Paramasivam Arumugam2؛ Vijayashree Priyadharsini Jayaseelan* 2
1Department of Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77
2Centre for Cellular and Molecular Research, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77
3Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77
چکیده
The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hospital, Tamil Nadu were included in this study. The participants were divided into control (n=50) and periodontitis (n=50) based on clinical examination. Blood samples were collected. Genotyping was performed using specific primers spanning the polymorphic site. The genotypic frequencies for the rs1695 polymorphism were not significantly different between cases and controls.
کلیدواژه‌ها
Genotype؛ GSTP؛ Periodontitis؛ Polymorphism
مراجع
  1. Ramachandra SS, Manchery N, Gupta VV. The aggressive periodontitis quandary: An appeal for naming consistency among researchers and clinicians. J Am Dent Assoc 2023;154:104-106.
  2. Balaji SK, Lavu V, Rao S. Chronic periodontitis prevalence and the inflammatory burden in a sample population from South India. Indian J Dent Res 2018;29:254-259.
  3. Reynolds MA. Modifiable risk factors in periodontitis: at the intersection of aging and disease. Periodontol 2000 2014;64:7-19.
  4. Albandar JM. Epidemiology and risk factors of periodontal diseases. Dent Clin North Am 2005;49:517-532.
  5. Jha A, Nath N, Kumari A, Kumari N, Panda AK, Mishra R. Polymorphisms and haplotypes of TLR-4/9 associated with bacterial infection, gingival inflammation/recession and oral cancer. Pathol Res Pract 2023;241:154284.
  6. Susmita S, Sanjeev K. Non-habit related oral squamous cell carcinoma: possible etiologic factors and probable prevention in indian scenario. Oral Surg Oral Med Oral Pathol Oral Radiol 2019;128:e90.
  7. Murthykumar K, Arjunkumar R, Jayaseelan VP. Association of vitamin D receptor gene polymorphism (rs10735810) and chronic periodontitis.  J Investig Clin Dent 2019; 10:e12440.
  8. Kavitha L, Vijayshree Priyadharshini J, Sivapathasundharam B. Association among interleukin-6 gene polymorphisms, type 2 diabetes mellitus, and chronic periodontitis: a pilot study. J Investig Clin Dent. 2017;8.
  9. Yang XR, Pfeiffer RM, Goldstein AM. Influence of glutathione-S-transferase (GSTM1, GSTP1, GSTT1) and cytochrome p450 (CYP1A1, CYP2D6) polymorphisms on numbers of basal cell carcinomas (BCCs) in families with the naevoid basal cell carcinoma syndrome. J Med Genet 2006;43:e16.
  10. Kiyohara C, Miyake Y, Koyanagi M, Fujimoto T, Shirasawa S, Tanaka K, Fukushima W, Sasaki S, Tsuboi Y, Yamada T, Oeda T, Miki T, Kawamura N, Sakae N, Fukuyama H, Hirota Y, Nagai M, Fukuoka Kinki Parkinson's Disease Study Group. GST polymorphisms, interaction with smoking and pesticide use, and risk for Parkinson's disease in a Japanese population. Parkinsonism Relat Disord 2010;16:447-452.
  11. Melén E, Nyberg F, Lindgren CM, Berglind N, Zucchelli M, Nordling E, Hallberg J, Svartengren M, Morgenstern R, Kere J, Bellander T, Wickman M, Pershagen G. Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease. Environ Health Perspect 2008;116:1077-1084.
  12. Saadat M. Evaluation of glutathione S-transferase P1 (GSTP1) Ile105Val polymorphism and susceptibility to type 2 diabetes mellitus, a meta-analysis. EXCLI J 2017;16:1188-1197.
  13. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
  14. Wang F, Zhang C, Zhu X, Zhang D, Zhang Z, Ni S, Wang Z, Xu S, Lan X, Ding Y, Liang L. Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by upregulating STAT3. Adv Clin Exp Med 2022;31:139-149.
  15. Xiao J, Wang Y, Wang Z, Zhang Y, Li Y, Xu C, Xiao M, Wang H, Guo S, Jin L, Wang J, Bao Y, Shang Y, Wu J. The relevance analysis of GSTP1 rs1695 and lung cancer in the Chinese Han population. Int J Biol Markers 2021;36:48-54.
  16. Baghaei A, Behjati M, Karimian A. Association Analysis of GSTP1-rs1695 Polymorphism with the Risk of Oral Cancer: A Literature Review, an Updated Meta- Analysis, and a Structural Assessment. Asian Pac J Cancer Prev 2022;23:3859-3868.
  17. Camargo Ortega VR, Bravo López LD, Visoso Salgado A, Mejia Sanchez F, Castillo Cadena J. Polymorphisms in Glutathione S-Transferase M1, T1, and P1 in Patients with Chronic Periodontitis: A Pilot Study. Int Sch Res Notices 2014;2014:135368.
  18. Yadav P, Banerjee A, Boruah N, Singh CS, Chatterjee P, Mukherjee S, Dakhar H, Nongrum HB, Bhattacharjee A, Chatterjee A. Glutathione S-transferasesP1 AA (105Ile) allele increases oral cancer risk, interacts strongly with c-Jun Kinase and weakly detoxifies areca-nut metabolites. Sci Rep 2020;10:6032.
  19. Krüger M, Hansen T, Kasaj A, Moergel M. The Correlation between Chronic Periodontitis and Oral Cancer. Case Rep Dent 2013;2013:262410.
  20. Fang C, Wei XM, Zeng XT, Wang FB, Weng H, Long X. Aberrant GSTP1 promoter methylation is associated with increased risk and advanced stage of breast cancer: a meta-analysis of 19 case-control studies. BMC Cancer 2015;15:920.
  21. Murthykumar K, Varghese S, Jayaseelan VP. Association of SRXN1 Receptor Gene Polymorphism with Susceptibility to Periodontitis. Contemp Clin Dent 2022;13:363-368.
آمار
تعداد مشاهده مقاله: 1,658
تعداد دریافت فایل اصل مقاله: 2,055


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب