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Molecular evidence, risk factors analysis, and hematological alterations associated with Theileria spp. spillover in captive wild mouflon sheep in Punjab, Pakistan | ||
| Iranian Journal of Veterinary Research | ||
| دوره 23، شماره 4 - شماره پیاپی 81، 2022، صفحه 349-357 اصل مقاله (553.87 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2022.43496.6362 | ||
| نویسندگان | ||
| M. Naveed1؛ M. Ijaz* 2؛ A. Ahmed3؛ N. Z. Ghumman1؛ M. Ishaq1؛ I. Muzammil3؛ M. U. Javed3 | ||
| 1M.Phil. in Veterinary Medicine, Department of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, Pakistan | ||
| 2Department of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, Pakistan | ||
| 3Ph.D. Student in Veterinary Medicine, Department of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, Pakistan | ||
| چکیده | ||
| Background: Landscape anthropization and interaction between domestic and wild animals are the major contributing factors involved in the emergence of new pathogens in wild animals. Theileriosis is an emerging issue of wild ungulates, especially in the tropical and subtropical areas of the globe. Aims: The current study investigated the mouflon sheep for Theileria infection using molecular methods and hematological analysis. Methods: This study was conducted on a total of 103 captive wild mouflon sheep present in eight different recreational zoos, and wildlife parks in Punjab, Pakistan to investigate the genotypic prevalence of Theileria spp. by targeting 18S rRNA and molecular evidence for Theileria spillover between domestic and wild mouflon sheep by phylogenetic analysis. The association of assumed risk factors and the effect of Theileria spp. on various hematological parameters were also assessed. Results: The results depicted that Theileria spp. was prevalent in 8 (7.77%, CI 95%: 3.99-14.59%), and 11 (10.68%, CI 95%: 06.07-18.12%) animals based on microscopy, and PCR, respectively. The phylogenetic analysis of the 18S rRNA gene of Theileria spp. from mouflon revealed a close resemblance with T. annulata from domestic animals. The risk factor analysis revealed that tick infestation, enclosure hygiene, previous tick infestation history, and the presence of wooden logs in the enclosure were significantly (P<0.05) associated with the occurrence of Theileria spp. infection in the captive mouflon sheep of Pakistan. Furthermore, a significant reduction in blood parameters like PCV, RBCs count, Hb, and platelets was observed in Theileria-positive animals. Conclusion: This study is the first evidence at the molecular level to characterize the spillover of Theileria spp. between the captive wild mouflon sheep and domestic animals of Pakistan, and it will be useful in developing control strategies for emerging theileriosis in captive wild animals. | ||
| کلیدواژهها | ||
| Emerging disease؛ Mouflon sheep؛ Phylogenetic analysis؛ Theileriosis؛ Wildlife | ||
| مراجع | ||
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Abid, K; Bukhari, S and Asif, M (2021). Molecular detection and prevalence of Theileria ovis and Anaplasma marginale in sheep blood samples collected from Layyah district in Punjab, Pakistan. Trop. Anim. Health Prod., 53: 1-9.
AbouLaila, M; AbdEl-Aziz, AR; Menshawy, S; Yokoyama, N; Igarashi, I; Al-Wabel, M and Omar, M (2021). Evaluation of the inhibitory effects of coumermycin A1 on the growth of Theileria and Babesia parasites in vitro and in vivo. Pak. Vet. J., 41: 469-474. https://doi.org/10.29261/ pakvetj/2021.064.
Adegoke, A; Kumar, D; Bobo, C; Rashid, MI; Durrani, AZ; Sajid, MS and Karim, S (2020). Tick-borne pathogens shape the native microbiome within tick vectors. Microorganisms. 8: 1-16. https://doi.org/10.3390/ microorganisms8091299.
Adjou Moumouni, PF; Guo, H; Gao, Y; Liu, M; Ringo, AE; Galon, EM; Vudriko, P; Umemiya-Shirafuji, R; Inoue, N; Suzuki, H and Xuan, X (2018). Identification and genetic characterization of Piroplasmida and Anaplasmataceae agents in feeding Amblyomma variegatum ticks from Benin. Vet. Parasitol. Reg. Stud. Reports. 14: 137-143. https://doi.org/10.1016/j.vprsr.2018. 10.006.
Ahmed, A; Ijaz, M; Ghauri, HN; Aziz, MU; Ghaffar, A; Naveed, M and Javed, MU (2020). Molecular evidence of Anaplasma infection in naturally affected domestic cats of Pakistan. Comp. Immunol. Microbiol. Infect. Dis., 72: 101524. https://doi.org/10.101 6/j.cimid.2020.101524.
Aktaş, M; Altay, K and Dumanli, N (2005). Survey of Theileria parasites of sheep in eastern Turkey using polymerase chain reaction. Small Rumin. Res., 60: 289-293.
Al-Fahdi, A; Alqamashoui, B; Al-Hamidhi, S; Kose, O; Tageldin, MH; Bobade, P; Johnson, EH; Hussain, AR; Karagenc, T and Tait, A (2017). Molecular surveillance of Theileria parasites of livestock in Oman. Ticks Tick Borne Dis., 8: 741-748. https://doi.org/10.1016/j.ttbdis. 2017.05.008.
Al-Hamidhi, S; Parveen, A; Iqbal, F; Asif, M; Akhtar, N; Elshafie, EI; Beja-Pereira, A and Babiker, HA (2022). Diversity and genetic structure of Theileria annulata in Pakistan and other endemic sites. Pathogens. 11: 334. https://doi.org/10.3390/pathogens11030334.
AL-Mayah, SH and Abdul-Karim, AT (2020). Epidemiology and seasonal variation of ixodid ticks and Piroplasmida detection in cattle of Basrah province, Iraq. Indian J. Forensic. Med. Toxicol., 14: 1391-1398.
Al-Saad, KM; AL-Amery, MAY; Hamed, TAAL and Muhsen, RK (2015). Babesiosis caballi in one-humped dromedaries of basrah province. Basrah. J. Vet. Res., 14: 207-214.
Ali, Z; Bibi, F; Mahel, AQ; Firdous, F and Zamaan, SU (2011). Captive breeding practices in Pakistan: A review. J. Anim. Plant. Sci., 21: 368-371.
Ali, S; Ijaz, M; Farooqi, SH; Durrani, AZ; Rashid, MI; Ghaffar, A; Ali, A; Rehman, A; Aslam, S and Khan, I (2019). Molecular characterisation of Theileria equi and risk factors associated with the occurrence of theileriosis in horses of Punjab (Pakistan). Equine Vet. Educ., 33: 75-83. https://doi.org/10.1111/eve.13161.
Ali, S; Ijaz, M; Ghaffar, A; Oneeb, M; Masud, A; Durrani, AZ and Rashid, MI (2020). Species distribution and seasonal dynamics of equine tick infestation in two subtropical climate niches in Punjab, Pakistan. Pak. Vet. J., 40: 25-30. http://dx.doi.org/10.29261/pakvetj/2019.095.
Altay, K; Aktaş, M and Dumanli, N (2004). Theileria infections in small ruminants in the east and southeast Anatolia. Turkiye Parazitol. Derg., 31: 268-271.
Altay, K; Dumanli, N; Holman, PJ and Aktas, M (2005). Detection of Theileria ovis in naturally infected sheep by nested PCR. Vet. Parasitol., 127: 99-104.
Alvarado-Rybak, M; Solano-Gallego, L and Millán, J (2016). A review of piroplasmid infections in wild carnivores worldwide: importance for domestic animal health and wildlife conservation. Parasit. Vectors. 9: 538. https://doi.org/10.1186/s13071-016-1808-7.
Basit, MA; Ijaz, M; Abbas, RZ; Khan, JA and Ashraf, K (2022). First molecular evidence of Ehrlichia infection: An emerging pathogen of small ruminants in Pakistan. Pak. Vet. J., 42: 208-214. http://dx.doi.org/10.29261/pakvetj/ 2022.012.
Batool, M (2019). Prevalence of tick infestation in farm animals from Punjab, Pakistan. Pak. Vet. J., 39: 406-410. https://doi.org/10.29261/pakvetj/2019.089.
Bell-Sakyi, L; Koney, EBM; Dogbey, O and Walker, AR (2004). Incidence and prevalence of tick-borne haemoparasites in domestic ruminants in Ghana. Vet. Parasitol., 124: 25-42.
Benfenatki, A; Bouacida, NSY; Oudhia, KA and Khelef, D (2016). Prevalence of Theileria equi infection in Algiers urban area using cELISA and microscopic examination. Asian J. Anim. Vet. Adv., 11: 511-515.
Boucher, F; Moutroifi, Y; Peba, B; Ali, M; Moindjie, Y; Ruget, AS; Abdouroihamane, S; Kassim, A; Soulé, M and Charafouddine, O (2020). Tick-borne diseases in the Union of the Comoros are a hindrance to livestock development: Circulation and associated risk factors. Ticks Tick Borne Dis., 11: 101283. https://doi.org/10.1016/j. ttbdis.2019.101283.
Ceylan, O; Uslu, A; Ceylan, C and Sevinc, F (2021). Predominancy of Rhipicephalus turanicus in tick-infested sheep from Turkey: A large-scale survey. Pak. Vet. J., 41: 429-433. https://doi.org/10.29261/pakvetj/2021.036.
Chen, Z; Liu, Q; Jiao, FC; Xu, BL and Zhou, XN (2014). Detection of piroplasms infection in sheep, dogs and hedgehogs in Central China. Infect. Dis., 3: 18. https://doi.org/10.1186/2049-9957-3-18.
Cicuttin, GL; Tarragona, EL; De Salvo, MN; Mangold, AJ and Nava, S (2015). Infection with Ehrlichia canis and Anaplasma platys (Rickettsiales: Anaplasmataceae) in two lineages of Rhipicephalus sanguineus sensu lato (Acari: Ixodidae) from Argentina. Ticks Tick Borne Dis., 6: 724-729. https://doi.org/10.1016/j.ttbdis.2015.06.006.
da Silveira, JAG; Rabelo, ÉML and Ribeiro, MFB (2011). Detection of Theileria and Babesia in brown brocket deer (Mazama gouazoubira) and marsh deer (Blastocerus dichotomus) in the State of Minas Gerais, Brazil. Vet. Parasitol., 177: 61-66.
Durrani, AZ; Younus, M; Kamal, N; Mehmood, N and Shakoori, AR (2011). Prevalence of ovine Theileria species in district Lahore, Pakistan. Pak. J. Zool., 43: 57-60.
Farooqi, SH; Ijaz, M; Saleem, MH; Rashid, MI; Ahmad, SS; Islam, S; Aqib, AI; Khan, A; Hussain, K and Khan, NU (2017). Prevalence and molecular diagnosis of Theileria annulata in bovine from three distincts zones of Khyber Pakhtunkhwa province, Pakistan. J. Anim. Plant. Sci., 27: 1836-1841.
Gebrekidan, H; Hailu, A; Kassahun, A; Rohoušová, I; Maia, C; Talmi-Frank, D; Warburg, A and Baneth, G (2014). Theileria infection in domestic ruminants in northern Ethiopia. Vet. Parasitol., 200: 31-38.
Ghafar, A; Cabezas-Cruz, A; Galon, C; Obregon, D; Gasser, RB; Moutailler, S and Jabbar, A (2020). Bovine ticks harbour a diverse array of microorganisms in Pakistan Parasit. Vectors. 13: 332. https://doi.org/10.1186/s13071-019-3862-4.
Ghauri, HN; Ijaz, M; Farooqi, SH; Ali, A; Ghaffar, A; Saleem, S; Iqbal, MK; Aziz, MU; Ghani, U; Ullah, MR and Ahmad, HM (2019). A comprehensive review on past, present and future aspects of canine theileriosis. Microb. Pathogen. 126: 116-122. https://doi.org/10.1016/j. micpath.2018.10.033.
Giangaspero, A; Marangi, M; Papini, R; Paoletti, B; Wijnveld, M and Jongejan, F (2015). Theileria sp. OT3 and other tick-borne pathogens in sheep and ticks in Italy: Molecular characterization and phylogeny. Ticks Tick Borne Dis., 6: 75-83. https://doi.org/10.1016/j.ttbdis.2014. 09.007.
Hassan, S; Skilton, RA; Pelle, R; Odongo, D; Bishop, RP; Ahmed, J; Seitzer, U; Bakheit, M; Hassan, SM and El Hussein, AM (2019). Assessment of the prevalence of Theileria lestoquardi in sheep from the Sudan using serological and molecular methods. Prev. Vet. Med., 169: 104697. https://doi.org/10.1016/j.prevetmed.2019.104697.
Hayati, MA; Hassan, SM; Ahmed, SK and Salih, DA (2020). Prevalence of ticks (Acari: Ixodidae) and Theileria annulata infection of cattle in Gezira State, Sudan. Parasite. Epidemiol. Control. 10: e00148. https://doi.org/10.1016/j. parepi.2020.e00148.
Hussain, MH; Saqib, M; Raza, F; Muhammad, G; Asi, MN; Mansoor, MK; Saleem, M and Jabbar, A (2014). Seroprevalence of Babesia caballi and Theileria equi in five draught equine populated metropolises of Punjab, Pakistan. Vet. Parasitol., 202: 248-256. https://doi.org/10. 1016/j.vetp ar.2014.01.026.
Hussein, AH; Mohammed, N and Mohammed, HK (2007). Theileriosis and babesiosis in cattle: haemogram and some biochemical parameters. Int. Soc. Anim. Hyg., 17: 143-150.
Ishaq, M; Ijaz, M; Lateef, M; Ahmed, A; Muzammil, I; Javed, MU; Raza, A and Ghumman, NZ (2022). Molecular characterization of Anaplasma capra infecting captive mouflon (Ovis gmelini) and domestic sheep (Ovis aries) of Pakistan. Small Rum. Res., 216: 106837. https://doi.org/10.1016/j.smallrumres.2022.106837.
Ito, TY; Lhagvasuren, B; Tsunekawa, A; Shinoda, M; Takatsuki, S; Buuveibaatar, B and Chimeddorj, B (2013). Fragmentation of the habitat of wild ungulates by anthropogenic barriers in Mongolia. PLoS One. 8: e56995.
Kundave, VR; Patel, AK; Patel, PV; Hasnani, JJ and Joshi, CG (2015). Detection of theileriosis in cattle and buffaloes by polymerase chain reaction. J. Parasit. Dis., 39: 508-513. https://doi.org/10.1007/s12639-013-0386-2.
Kurtenbach, K; Hanincová, K; Tsao, JI; Margos, G; Fish, D and Ogden, NH (2006). Fundamental processes in the evolutionary ecology of Lyme borreliosis. Nat. Rev. Microbiol., 4: 660-669. https://doi.org/10.1038/ nrmicro1475.
Mans, BJ; Pienaar, R and Latif, AA (2015). A review of Theileria diagnostics and epidemiology. Int. J. Parasitol. Parasites. Wildl., 4: 104-118. https://doi.org/10.1016/j. ijppaw.2014.12.006.
Mohammed, OB; Jarelnabi, AA; Aljumaah, RS; Alshaikh, MA; Bakhiet, AO; Omer, SA; Alagaili, AN and Hussein, MF (2014). Coxiella burnetii, the causative agent of Q-fever in Saudi Arabia: molecular detection from camel and other domestic livestock. Asian Pac. J. Trop. Med., 7: 715-719. https://doi.org/10.1016/S1995-7645(14)60122-X.
Nasreen, A; Niaz, S; Hassan, M; Khan, A; Ahmed, H; Khattak, I; Zeb, J; Naeem, H and Hassan, MA (2020). Molecular detection of small ruminant piroplasmosis and first report of Theileria luwenshuni (Apicomplexa: Theileridae) in small ruminants of Pakistan. Exp. Parasitol., 212: 107872. https://doi.org/10.1016/j.exppara.2020. 107872.
Naz, S; Maqbool, A; Ahmed, S; Ashraf, K; Ahmed, N; Saeed, K; Latif, M; Iqbal, J; Ali, Z and Shafi, K (2012). Prevalence of theileriosis in small ruminants in Lahore-Pakistan. J. Vet. Anim. Sci., 2: 16-20.
Nazifi, S; Razavi, SM; Kianiamin, P and Rakhshandehroo, E (2011). Evaluation of erythrocyte antioxidant mechanisms: antioxidant enzymes, lipid peroxidation, and serum trace elements associated with progressive anemia in ovine malignant theileriosis. Parasitol. Res., 109: 275-281.
Niaz, S; Ur Rahman, Z; Ali, I; Cossío-Bayúgar, R; Amaro-Estrada, I; Alanazi, AD; Khattak, I; Zeb, J; Nasreen, N and Khan, A (2021). Molecular prevalence, characterization and associated risk factors of Anaplasma spp. and Theileria spp. in small ruminants in Northern Pakistan. Parasite. 28: 3. https://doi.org/10.1051/parasite/ 2020075.
Nijhof, AM; Penzhorn, BL; Lynen, G; Mollel, JO; Morkel, P; Bekker, CPJ and Jongejan, F (2003). Babesia bicornis sp. nov. and Theileria bicornis sp. nov.: Tick-borne parasites associated with mortality in the black rhinoceros (Diceros bicornis). J. Clin. Microbiol., 41: 2249-2254. https://doi.org/10.1128/JCM.41.5.2249-2254.2003.
Ola-Fadunsin, SD; Sharma, RSK; Abdullah, DA; Gimba, FI; Jesse, FFA and Sani, RA (2020). Molecular detection, prevalence and risk factors of Theileria orientalis infection among cattle in Peninsular Malaysia. Prev. Vet. Med., 180: 105027. https://doi.org/10.1016/j.prevetmed.2020.10 5027.
Oludairo, OO; Aiyedun, JO; Olorunshola, ID; Dibal, MA; Gungbias, AA; Ayeni, AMJ and Adeyi, AJ (2016). Transboundary diseases and wildlife management: an overview. Bangladesh J. Vet. Med., 14: 123-130.
Omer, OH; El-Malik, KH; Mahmoud, OM; Haroun, EM; Hawas, A; Sweeney, D and Magzoub, M (2002). Haematological profiles in pure bred cattle naturally infected with Theileria annulata in Saudi Arabia. Vet. Parasitol., 107: 161-168. https://doi.org/10.1016/s0304-4017(02)000 94-8.
Oryan, A; Namazi, F; Sharifiyazdi, H; Razavi, M and Shahriari, R (2013). Clinicopathological findings of a natural outbreak of Theileria annulata in cattle: an emerging disease in southern Iran. Parasitol. Res., 112: 123-127. https://doi.org/10.1007/s00436-012-3114-4.
Penzhorn, BL (2006). Babesiosis of wild carnivores and ungulates. Vet. Parasitol., 138: 11-21.
Posada-Guzm, M; Fernanda, G and Romero-Zúñiga, JJ (2015). Detection of Babesia caballi and Theileria equi in blood from equines from four indigenous communities in Costa Rica. Vet. Med. Int., 2015: 236278. https://doi.org/ 10.1155/2015/236278.
Radostits, OM; Gay, CC; Hinchcliff, KW and Constable, PD (2006). Veterinary medicine E-book: A textbook of the diseases of cattle, horses, sheep, pigs and goats. 11th Edn., Elsevier Health Sciences. Volume.
Ramos, CA; Ramos, RA; Araujo, FR; Guedes, DS; Souza, II; Ono, TM; Vieira, AS; Pimentel, DS; Rosas, EO and Faustino, MA (2009). Comparison of nested-PCR with blood smear examination in detection of Ehrlichia canis and Anaplasma platys in dogs. Braz. J. Vet. Parasitol., 18: 58-62.
Razavi, SM; Nazifi, S; Bateni, M and Rakhshandehroo, E (2011). Alterations of erythrocyte antioxidant mechanisms: antioxidant enzymes, lipid peroxidation and serum trace elements associated with anemia in bovine tropical theileriosis. Vet. Parasitol., 180: 209-214.
Razmi, GR; Eshrati, H and Rashtibaf, M (2006). Prevalence of Theileria spp. infection in sheep in South Khorasan province, Iran. Vet. Parasitol., 140: 239-243.
Riaz, M and Tasawar, Z (2017). A study on molecular surveillance of Theileria spp. infection and its impact on hematological and biochemical changes in naturally infected small ruminants at Multan, Pakistan. Pure Appl. Biol., 6: 1427-1435.
Saeed, S; Jahangir, M; Fatima, M; Shaikh, RS; Khattak, RM; Ali, M and Iqbal, F (2015). PCR based detection of Theileria lestoquardi in apparently healthy sheep and goats from two districts in Khyber Pukhtoon Khwa (Pakistan). Trop. Biomed., 32: 225-232.
Salih, DA; ElHussein, AM; Hayat, M and Taha, KM (2003). Survey of Theileria lestoquardi antibodies among Sudanese sheep. Vet. Parasitol., 111: 361-367. https://doi.org/10. 1016/S030 4-4017(02)00389-8.
Sandhu, GS; Grewal, AS; Singh, A; Kondal, JK; Singh, J and Brar, RS (1998). Haematological and biochemical studies on experimental Theileria annulata infection in crossbred calves. Vet. Res. Commun., 22: 347-354. https://doi.org/10.1023/a:1006129306093.
Shabbir, MZ and Khan, JA (2010). Prevalence of theileriosis in sheep in Okara district, Pakistan. Pak. J. Zool., 42: 639-643.
Shah, MH; Ijaz, M; Ahmed, A; Aziz, MU; Ghaffar, A; Ghauri, HN and Naveed, M (2020). Molecular analysis and risk factors associated with Theileria equi infection in domestic donkeys and mules of Punjab, Pakistan. J. Equine Vet. Sci., 92: 103164. https://doi.org/10.1016/j.jevs.2020. 103164.
Shiono, H; Yagi, Y; Kumar, A; Yamanaka, M and Chikayama, Y (2004). Accelerated binding of autoantibody to red blood cells with increasing anaemia in cattle experimentally infected with Theileria sergenti. J. Vet. Med. Ser. B., 51: 39-42.
Taha, KM; Salih, DA; Ali, AM; Omer, RA and El Hussein, AM (2013). Naturally occurring infections of cattle with Theileria lestoquardi and sheep with Theileria annulata in the Sudan. Vet. Parasitol., 191: 143-145. https://doi.org/10. 1016/j.vetpar.2012.08.003. Thrusfield, MV (2007). Veterinary epidemiology. 4th Edn., Oxford, Ames, Iowa: Blackwell Science.
Valdez, R (2008). Ovis orientalis. IUCN red List Threat species. e.T15739A5076068.
Weir, W; Karagenç, T; Gharbi, M; Simuunza, M; Aypak, S; Aysul, N; Darghouth, MA; Shiels, B and Tait, A (2011). Population diversity and multiplicity of infection in Theileria annulata. Int. J. Parasitol., 41: 193-203. https://doi.org/10.1016/j.ijpara.2010.08.004.
Zaeemi, M; Haddadzadeh, H; Khazraiinia, P; Kazemi, B and Bandehpour, M (2011). Identification of different Theileria species (Theileria lestoquardi, Theileria ovis, and Theileria annulata) in naturally infected sheep using nested PCR-RFLP. Parasitol. Res., 108: 837-843.
Zaman, MA; Rafique, A; Mehreen, U; Mehnaz, S; Atif, FA; Abbas, A; Hussain, K; Raza, MA; Altaf, S; Siddique, F and Masudur, RM (2022). Epidemiological investigation and development of loop mediated isothermal amplification for the diagnosis of ovine theileriosis. Pak. Vet. J., 42: 370-375. http://dx.doi.org/10.29261/pakvetj/2022.039.
Zobba, R; Chisu, V; Pinna Parpaglia, ML; Spezzigu, A; Masala, G; Schianchi, E and Alberti, A (2020). Molecular characterization and phylogenetic analysis of Babesia and Theileria spp. in Sardinian ruminants. Vet. Parasitol. Reg. Stud. Reports. 22: 100453. https://doi.org/ 10.1016/j.vp rsr.2020.100453. | ||
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