| تعداد نشریات | 24 |
| تعداد شمارهها | 917 |
| تعداد مقالات | 8,230 |
| تعداد مشاهده مقاله | 16,274,710 |
| تعداد دریافت فایل اصل مقاله | 13,751,989 |
Association of temperament with genetic polymorphisms in SOD1, GSTM1 and GSTT1 genes | ||
| Molecular Biology Research Communications | ||
| دوره 10، شماره 1، 2021، صفحه 33-38 اصل مقاله (234.82 K) | ||
| نوع مقاله: Original article | ||
| شناسه دیجیتال (DOI): 10.22099/mbrc.2020.38820.1565 | ||
| نویسندگان | ||
| Zahra Zendehboodi* ؛ Zahra Saberikia | ||
| Department of Biology, College of Sciences, Shiraz University, Shiraz 71467-13565, Iran | ||
| چکیده | ||
| Due to its accessibility, efficacy, and affordability, traditional medicine (TM) is the main source of health services for many people in the world. Nevertheless, in spite of its benefits, there are still many issues about the principles of TM which demand further declaration. One of the essential principles of Iranian traditional medicine (ITM) is temperament (mizaj), which efficiently applied in diagnosis and therapy of illnesses. In this study we aimed to explore the association of GSTM1/T1, and SOD1 50 bp Ins/Del polymorphisms with combined groups of temperament. The study was conducted in 217 healthy males from Fars province, southern Iran. The self-reported mizaj questionnaire was applied to identify the participants’ temperament. Then individuals with temperate, warm/moist, and warm/dry temperament were entered in the study. To determine the genotype of GSTM1, GSTT1, and SOD1, the polymerase chain reaction (PCR)-based method was performed. As the results of χ2 analysis showed, the frequency of GSTT1, GSTM1, and SOD1 polymorphisms in temperate group was not significantly differ from that in each of warm/moist and warm/dry groups. Further research with larger samples are suggested to clarify the association between temperament and biomolecular features. | ||
| کلیدواژهها | ||
| Temperament؛ GSTT1؛ GSTM1؛ SOD1؛ polymorphism | ||
| مراجع | ||
|
1. Movahhed M, Mosaddegh M, Farsani G, Abolhasani M. History of fatty liver in mediecal Iranian medicine. HealthMED 2013;7:786-792. 2. Mojahedi M, Naseri M, Majdzadeh R, Ebadiani M, Keshavarz M, Nazem E, Khodadoost M, Mozaffarpur SA. [A review on identification mizaj (temperament) indices in Iranian traditional medicine (ITM)]. Hist Med J (Quart) 2012;4:37-76. [In Persian] 3. Yousefifard M, Parviz M, Hosseini M, Ebadiani M, Keshavarz M. [Mizaj; past, present and future]. Physiol Pharmacol 2013;16:328-339. [In Persian] 4. Allocati N, Masulli M, Di Ilio C, Federici L. Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases. Oncogenesis 2018;7:8. 5. Khalighinasab MR, Saify K, Saadat M. Association between GSTM1 and GSTT1 polymorphisms and susceptibility to methamphetamine dependence. Mol Biol Res Commun 2015;4:25-32. 6. Saify K, Khalighinasab MR, Saadat M. No association between GSTM1 and GSTT1 genetic polymorphisms and susceptibility to opium sap dependence. Mol Biol Res Commun 2016;5: 59-64. 7. Ighodaro OM, Akinloye OA. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid. Alexandria J Med 2018;54:287-293. 8. Circu ML, Aw TY. Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med 2010;48:749-762. 9. Broom WJ, Greenway M, Sadri-Vakili G, Russ C, Auwarter KE, Glajch KE, Dupre N, Swingler RJ, Purcell S, Hayward C, Sapp PC, McKenna-Yasek D, Valdmanis PN, Bouchard JP, Meininger V, Hosler BA, Glass JD, Polack M, Rouleau GA, Cha JH, Hardiman O, Brown RH Jr. 50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2008;9:229-237. 10. Saify K, Saadat M. Influence of a 50bp Ins/Del polymorphism at promoter of the superoxide dismutase-1 on gene expression and risk of heroin dependency. Environ Health Prev Med 2017;22:4. 11. Mirsadraee N, Saadat M. Association between a 50bp Ins/Del polymorphism at the promoter region of the superoxide dismutase-1 and age of onset of schizophrenia. EXCLI J 2019;18: 204-206. 12. Kordestanian N, Saadat M. A 50-bp Ins/Del polymorphism at the promoter region of the superoxide dismutase-1 and bipolar disorder type 1. Nord J Psychiatry 2017;71:570-573. 13. Eskandari-Nasab E, Kharazi-Nejad E, Nakhaee A, Afzali M, Tabatabaei SP, Tirgar-Fakheri K, Hashemi M. 50-bp Ins/Del polymorphism of SOD1 is associated with increased risk of cardiovascular disease. Acta Med Iran 2014;52:591-595. 14. Darroudi S, Tajbakhsh A, Esmaily H, Ghazizadeh H, Zamani P, Sadabadi F, Tayefi M, Tayefi B, Fereydouni N, Mouhebati M, Akbari Sark N, Avan A, Ferns GA, Mohammadpour AH, Asadi Z, Ghayour-Mobarhan M. 50 bp deletion in promoter superoxide dismutase 1 gene and increasing risk of cardiovascular disease in Mashhad stroke and heart atherosclerotic disorder cohort study. Biofactors 2020;46:55-63. 15. Ebrahimpour S, Saadat I. Association of CAT C-262T and SOD1 A251G single nucleotide polymorphisms susceptible to gastric cancer. Mol Biol Res Commun 2014;3:223-229. 16. Jamhiri I, Saadat I, Omidvari S. Genetic polymorphisms of superoxide dismutase-1 A251G and catalase C-262T with the risk of colorectal cancer. Mol Biol Res Commun 2017;6:85-90. 17. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007;35:495-516. 18. Zendehboodi Z. Comparison of cytological parameters of exfoliated buccal mucosal cells in different temperament groups. J Kermanshah Univ Med Sci 2017;21:27-31. 19. Redza-Dutordoir M, Averill-Bates DA. Activation of apoptosis signalling pathways by reactive oxygen species. Biochim Biophys Acta 2016;1863:2977-2992. 20. Tang H, Tian E, Liu C, Wang Q, Deng H. Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones. PLoS One 2013;8:e59610. 21. Coluzzi E, Colamartino M, Cozzi R, Leone S, Meneghini C, O'Callaghan N, Sgura A. Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells. PLoS One 2014;9:e110963. 22. Zendehboodi Z. Association of glutathione S-transferase M1 and T1 polymorphisms and temperament. Mol Biol Res Commun 2017;6:95-100. 23. Zendehboodi Z. Association between 50 bp insertion/deletion polymorphism in promoter of the superoxide dismutase-1 and temperament. Int J Basic Sci Med 2018;3:59-62. 24. Mojahedi M, Naseri M, Majdzadeh R, Keshavarz M, Ebadini M, Nazem E, Saberi Isfeedvajani M. Reliability and validity assessment of mizaj questionnaire: a novel self-report scale in Iranian traditional medicine. Iran Red Crescent Med J 2014;16:e15924. 25. Newton CR (1995) Mutational analysis: known mutations. In: McPherson MJ, Hames D, Taylor GR (eds) PCR2: a practical approach. IRL-Press, Oxford, pp 219-222. 26. Rabelo-Santos SH, Zeferino L, Villa LL, Sobrinho JP, Amaral RG, Magalhães AV. Human papillomavirus prevalence among women with cervical intraepithelial neoplasia III and invasive cervical cancer from Goiânia, Brazil. Mem Inst Oswaldo Cruz 2003;98:181-184. 27. Ivaschenko T, Sideleva O, Baranov V. Glutathione-S-transferase µ and theta gene polymorphisms as new risk factors of atopic bronchial asthma. J Mol Med 2002;80:39-43. 28. Organization WH. WHO traditional medicine strategy 2014-2023, World Health Organization; 2013. 29. Li S, Zhang ZQ, Wu LJ, Zhang XG, Li YD, Wang YY. Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network. IET Syst Biol 2007;1:51-60. 30. Ma T, Tan C, Zhang H, Wang M, Ding W, Li S. Bridging the gap between traditional Chinese medicine and systems biology: the connection of cold syndrome and NEI network. Mol Biosyst 2010;6:613-619. 31. Chen G, Lu C, Zha Q, Xiao C, Xu S, Ju D, Zhou Y, Jia W, Lu A. A network-based analysis of traditional Chinese medicine cold and hot patterns in rheumatoid arthritis. Complement Ther Med 2012;20:23-30. 32. Rezadoost H, Karimi M, Jafari M. Proteomics of hot-wet and cold-dry temperaments proposed in Iranian traditional medicine: a Network-based Study. Sci Rep 2016;6:30133. | ||
|
آمار تعداد مشاهده مقاله: 2,083 تعداد دریافت فایل اصل مقاله: 1,091 |
||