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Estimation of periostin as a biomarker for early pregnancy diagnosis in goats: a preliminary study | ||
| Iranian Journal of Veterinary Research | ||
| دوره 22، شماره 1 - شماره پیاپی 74، 2021، صفحه 72-75 اصل مقاله (245.37 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2020.38499.5606 | ||
| نویسندگان | ||
| A. M. Köse* 1؛ M. K. Sarıbay1؛ E. Koldaş Ürer1؛ Z. Naseer2؛ G. Doğruer1؛ F. Karaca3؛ N. Coşkun Çetin3 | ||
| 1Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, TR-31040, Hatay, Turkey | ||
| 2Department of Clinical Studies, Faculty of Veterinary and Animal Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, 46000, Pakistan | ||
| 3Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, TR-31040, Hatay, Turkey | ||
| چکیده | ||
| Background: Periostin (POSTN) is an extracellular matrix (ECM) protein that plays an important role in the metastatic process and cancer cell migration. As implantation is a similar mechanism to metastasis, it has been hypothesized that POSTN may also play a role in the implantation process. Aims: The aim of the present study was to compare POSTN and progesterone levels during the early pregnancy stage in Damascus goats. Methods: Forty goats were synchronized using progesterone based sponges and were mated upon estrus signs display. While ten goats were kept as control (CON) and were not allowed to mate. Blood samples were taken through jugular venepuncture from CON and synchronized goats on day 13, 15, 17, 19, and 21 of breeding. Progesterone and POSTN levels were determined by enzyme-linked immunosorbent assay (ELISA). Later the pregnancy diagnosis was confirmed by transabdominal ultrasonography on day 50 after mating. Results: Progesterone level was influenced by status of pregnancy and day of observation with an interaction between the status of pregnancy and day of observation in goats. Whereas POSTN level was only affected by the day of observation. Conclusion: POSTN level did not vary with progesterone level during phase of embryonic implantation in goats; however, standardization and application of different procedures for POSTN assay in a large group of animals might be useful as an early pregnancy biomarker in goats. | ||
| کلیدواژهها | ||
| Biomarker؛ Goat؛ Periostin؛ Pregnancy؛ Progesterone | ||
| مراجع | ||
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Ahn, HW; Farmer, JL; Bazer, FW and Spencer, TE (2009). Progesterone and interferon tau-regulated genes in the ovine uterine endometrium: identification of periostin as a potential mediator of conceptus elongation. Reproduction. 138: 813-825. doi: 10.1530/REP-09-0208. Al-Merestani, M; Zarkawi, M and Wardeh, M (2003). Improving there productive efficiency, pregnancy diagnosis and monitoring the resumption of luteal activity in indigenous Damascus goats. Reprod. Dom. Anim., 38: 36-40. doi: 10.1046/j.1439-0531.2003.00394.x. Bazer, FW; Vallet, JL; Roberts, RM; Sharp, DC and Thatcher, WW (1986). Role of conceptus secretory products in establishment of pregnancy. J. Reprod. Fert., 76: 841-850. doi: 10.1530/jrf.0.0760841. Boscos, CM; Samartzi, FC; Lymberopoulos, AG; Stefanakis, A and Belibasaki, S (2003). Assessment of progesterone concentration using enzyme immunoassay, for early pregnancy diagnosis in sheep and goats. Reprod. Dom. Anim., 38: 170-174. doi: 10.1046/j.1439-0531.2003.00407.x. Chao, LM; Takayama, K; Nakanishi, Y; Hamana, K; Takagi, M; Kubota, C and Kojima, T (2008). Luteal life span and fertility after estrus synchronization in goats. J. Vet. Sci., 9: 95-101. doi: 10.4142/jvs.2008.9.1.95. Di Cello, A; Rania, E; DiSanzo, M; D Alessandro, P; Venturella, R; Strina, I; Quaresima, B; Morelli, M; Engeland, IV; Waldeland, H; Andresen, O and Tverdal, A (1997). Foetal loss in dairy goats: an epidemiological study in 515 individual goats. Anim. Reprod. Sci., 49: 45-53. doi: 10.1016/s0378-4320(97)00059-6. Erdem, H and Sarıbay, MK (2012). Pregnancy and detection methods. In: Semacan, A; Kaymaz, M; Fındık, M; Rişvanlı, A and Köker, A (Eds.), Obstetrics and gyneacology in farm animals. (1st Edn.), Malatya, Medipres. PP: 507-521. Freis, A; Schlegel, J; Kuon, RJ; Doster, A; Jauckus, J; Strowitzki, T and Germeyer, A (2017). Serum periostin levels in early in pregnancy are significantly altered in women with miscarriage. Reprod. Biol. Endocrinol., 15: 1-6. doi: 10.1186/s12958-017-0307-9. Gaafar, KM;Gabr, MK and Teleb, DF (2005). The hormonal profile during the estrous cycle and gestation in Damascus goats. Small Rumin. Res., 57: 85-93. doi: 10.1016/j.smallrumres.2004.07.009. Gillan, L; Matei, D and Fishman, DA (2002). Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V) beta(3) and alpha(V) beta(5) integrins and promotes cell motility. Cancer Res., 62: 5358-5364. Hamilton, DW (2008). Functional role of periostin expression in development and wound repair: implications for connective tissue disease. J. Cell Commun. Signal., 2: 9-17. doi: 10.1007/s12079-008-0023-5. Hiroi, H; Momoeda, M; Nakazawa, F; Koizumi, M; Tsutsumi, R; Hosokawa, Y; Osuga, Y; Yano, T; Tsutsumi, O and Taketani, Y (2007). Expression and regulation of periostin/OSF-2 gene in rat uterus and human endometrium. Endocr. J., 0802060060-0802060060. doi: 10.1507/endocrj.k07-073. Khanum, SA; Hussain, M and Kausar, R (2008). Progesterone and estradiol profiles during estrous cycle and gestation in dwarf goats (Capra hircus). Pakistan Vet. J., 28: 1-4. Morelli, M; Misaggi, R; Di Cello, A; Zuccala, V; Costanzo, F; Zullo, F and Quaresima, B (2014). Tissue expression and serum levels of periostin during pregnancy: a new biomarker of embryo-endometrial cross talk at implantation. Eur. J. Obstet. Gynecol. Reprod. Biol., 175: 140-144. doi: 10.1016/j.ejogrb.2013.12.027. Rios, H; Koushik, SV; Wang, H; Wang, J; Zhou, HM; Lindsley, A; Rogers, R; Chen, Z; Maeda, M; Kruzynska-Frejtag, A; Feng, JQ and Conway, SJ (2005). Periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol. Cell. Biol., 25: 11131-11144. doi: 10.1128/MCB.25.24.11131-11144.2005. Savaris, RF; Hamilton, AE; Lessey, BA and Giudice, LC (2008). Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy. Reprod. Sci., 15: 797-816. doi: 10.1177/1933719108317585. Thibier, M; Pothelet, D; Jeanguyot, N and de Montigny, G (1981). Estrous behavior, progesterone in peripheral plasma and milk in dairy goats at onset of breeding season. J. Dairy Sci., 64: 513-519. doi: 10.3168/jds.S0022-0302(81)82601-X. Thorburn, GD and Schneider, W (1972). The progesterone concentration in the plasma of the goat during the oestrus cycle and pregnancy. J. Endocrinol., 52: 23-36. doi: https://doi.org/10.1677/joe.0.0520023 | ||
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