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Kirtipal, Nikhil, Thakur, Hitender, Sobti, Ranbir Chander, Janmeja, Ashok Kumar. (1399). Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population. , 9(2), 41-43. doi: 10.22099/mbrc.2019.34594.1431
Nikhil Kirtipal; Hitender Thakur; Ranbir Chander Sobti; Ashok Kumar Janmeja. "Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population". , 9, 2, 1399, 41-43. doi: 10.22099/mbrc.2019.34594.1431
Kirtipal, Nikhil, Thakur, Hitender, Sobti, Ranbir Chander, Janmeja, Ashok Kumar. (1399). 'Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population', , 9(2), pp. 41-43. doi: 10.22099/mbrc.2019.34594.1431
Kirtipal, Nikhil, Thakur, Hitender, Sobti, Ranbir Chander, Janmeja, Ashok Kumar. Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population. , 1399; 9(2): 41-43. doi: 10.22099/mbrc.2019.34594.1431

Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population

Molecular Biology Research Communications
مقاله 1، دوره 9، شماره 2، 2020، صفحه 41-43    اصل مقاله (177.09 K)
نوع مقاله: Short communication
شناسه دیجیتال (DOI): 10.22099/mbrc.2019.34594.1431
نویسندگان
Nikhil Kirtipal* 1؛ Hitender Thakur1، 2؛ Ranbir Chander Sobti1؛ Ashok Kumar Janmeja3
1Department of Biotechnology, Panjab University, Chandigarh-160014, India
2Assistant Professor, Dept. of Biotechnology, SUSCET, Tangori, Punjab-140306, India
3Respiratory Medicine, MMCH, Solan, Himachal Pradesh, India
چکیده
Interleukin-6 (IL6) is encoded by the IL6 gene in human and acts as pro-inflammatory cytokine and an anti-inflammatory cytokine. Recent studies established that IL6 substantially contribute in the diagnosed of systemic inflammation for the patients suffering from lung diseases such as chronic obstructive pulmonary disease (COPD). Thereof, this work aimed to investigate the protagonist of IL6 (-174 G/C) genotypes as an essential risk factor for COPD in north Indian population. In the study, a total of 200 clinically diagnosed patients with COPD were selected against 200 patients. Statistical analysis reveleaed that there was no significant association between the  IL6 -174 G/C genetic polymorphism and the risk of COPD (P>0.05).
کلیدواژه‌ها
Chronic obstructive pulmonary disease؛ Interleukin-6؛ Genotypes؛ Cytokine
مراجع

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