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Disposition kinetics of orbifloxacin in tissues of crucian carp (Carassius auratus) following a single intramuscular administration | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 8، دوره 20، شماره 2 - شماره پیاپی 67، 2019، صفحه 131-135 اصل مقاله (215.94 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2019.5263 | ||
| نویسندگان | ||
| Y. R. Yang* 1؛ F. Yang2؛ N. Sun3؛ G. Y. Wang2 | ||
| 1College of Biology and Food Engineering, Huanghuai University, Zhumadian 463000, China | ||
| 2Department of Basic Veterinary Medicine, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471023, China | ||
| 3Key Laboratory of Special Animal Epidemic Disease, Institute of Special Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun 130112, Jilin, China | ||
| چکیده | ||
| Background: Orbifloxacin is being widely used in China to treat fish infections in an extra-label manner, which may cause its potential residues in edible tissues. Aims: The purpose of this study was to determine the disposition kinetics of orbifloxacin in crucian carp (Carassius auratus) following intramuscular administration for its further safe application in aquaculture industry. Methods: Tissue samples of skin, muscle, kidney, and liver were collected from six crucian carps reared at 25°C at 5, 10, 15, 30, 45 min, 1, 2, 4, 6, 12, 24, 48, 72, and 96 h following a single intramuscular injection at 7.5 mg/kg body weight (BW). The orbifloxacin concentrations in tissues were determined using a high-performance liquid chromatography (HPLC) method with a fluorescence detector, then average concentrations versus time data were subjected to non-compartmental analysis to obtain the kinetic parameters. Results: The peak concentration of 5.68 ± 0.03 µg/g was calculated in kidney at 2 h, followed by muscle (5.51 ± 0.01 µg/g) at 4 h, liver (4.84 ± 0.20 µg/g) at 2 h, and skin (4.27 ± 0.08 µg/g) at 4 h. Area under concentration-time curve was calculated as 79.22, 94.72, 118.65, and 129.02 h·µg/g in kidney, liver, skin, and muscle, respectively. And the elimination half-lives were determined as 18.17, 18.41, 18.77, and 19.11 h in skin, kidney, muscle, and liver, respectively. Conclusion: It was shown that orbifloxacin was well distributed into tissues while relatively slowly eliminated in crucian carp reared at 25°C following a single intramuscular injection. | ||
| کلیدواژهها | ||
| Crucian carp؛ Disposition kinetics؛ Intramuscular injection؛ Orbifloxacin؛ Tissue depletion | ||
| مراجع | ||
|
Abd El-Aty, AM; Choi, JH; Ko, MW; Khay, S; Goudah, A; Shin, HC; Kim, JS; Chang, BJ; Lee, CH and Shim, JH (2009). Approaches for application of sub and supercritical fluid extraction for quantification of orbifloxacin from plasma and milk: application to disposition kinetics. Anal. Chim. Acta. 631: 108-115.
Cazedey, ECL and Salgado, HRN (2013). Orbifloxacin: a review of properties, its antibacterial activities, pharmacokinetic/pharmacodynamic characteristics, therapeutic use, and analytical methods. Crit. Rev. Anal. Chem., 43: 79-99.
Ding, FK; Cao, JY; Ma, LB; Pan, QS; Fang, ZP and Lu, XC (2006). Pharmacokinetics and tissue residues of difloxacin in crucian carp (Carassius auratus) after oral administration. Aquaculture. 256: 121-128.
Elema, MO; Hoff, KA and Kristensen, HG (1994). Multiple-dose pharmacokinetic study of flumequine in Atlantic Salmon (Salmo-Salar L). Aquaculture. 128: 1-11.
Engberg, J; Aarestrup, FM; Taylor, DE; Gerner-Smidt, P and Nachamkin, I (2001). Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates. Emerg. Infect. Dis., 7: 24-34.
Fan, YC; Sheu, SY; Lai, HT; Chang, MH; Chen, PH; Lei, YC; Kuo, TF and Wang, CY (2015). Residue depletion study of danofloxacin in cultured tilapia (Oreochromis mossambicus). J. AOAC Int., 98: 575-579.
Goudah, A and Abo-El-Sooud, K (2008). Pharmacokinetics and milk penetration of orbifloxacin after intravenous and intramuscular injections to dromedary lactating camels (Camelus dromedaries). J. Vet. Pharmacol. Ther., 31: 276-280.
Goudah, A; Cho, HJ; Shin, HC; Shim, JH; Regmi, NL; Shimoda, M and Abd El-Aty, AM (2009). Pharmacokinetics and milk distribution characteristics of orbifloxacin following intravenous and intramuscular injection in lactating ewes. J. Vet. Pharmacol. Ther., 32: 338-344.
Haines, GR; Brown, MP; Gronwall, RR; Merritt, KA and Baltzley, LK (2001). Pharmacokinetics of orbifloxacin and its concentration in body fluids and in endometrial tissues of mares. Can. J. Vet. Res., 65: 181-187.
Hnot, ML; Cole, LK; Lorch, G; Rajala-Schultz, PJ and Papich, MG (2015). Effect of feeding on the pharmacokinetics of oral minocycline in healthy research dogs. Vet. Dermatol., 26: 399-405.
Intorre, L; Cecchini, S; Bertini, S; Varriale, AMC; Soldani, G and Mengozzi, G (2000). Pharmacokinetics of enrofloxacin in the seabass (Dicentrarchus labrax). Aquaculture. 182: 49-59.
Kay-Mugford, PA; Weingarten, AJ; Ngoh, M; Zolynas, R; White, A; Katz, T; Simmons, R and Varma, KJ (2002). Determination of plasma and skin concentrations of orbifloxacin in dogs with clinically normal skin and dogs with pyoderma. Vet. Ther., 3: 402-408.
Li, C; Fu, Y; Long, X and Liu, X (2008). In vitro antibacterial effect of orbifloxacin on pathogenic bacteria in aquaculture industy. Progress Vet. Med., 29: 46-49 (in Chinese).
Lucchetti, D; Fabrizi, L; Guandalini, E; Podesta, E; Marvasi, L; Zaghini, A and Coni, E (2004). Long depletion time of enrofloxacin in rainbow trout (Oncorhynchus mykiss). Antimicrob. Agents Chemother., 48: 3912-3917.
Marin, P; Escudero, E; Fernandez-Varon, E and Carceles, CM (2007). Pharmacokinetics and milk penetration of orbifloxacin after intravenous, subcutaneous, and intramuscular administration to lactating goats. J. Dairy Sci., 90: 4219-4225.
Martinez, M; McDermott, P and Walker, R (2006). Pharmacology of the fluoroquinolones: a perspective for the use in domestic animals. Vet. J., 172: 10-28.
Martinsen, B; Horsberg, TE and Burke, M (1994). Multiple-dose pharmacokinetic and depletion studies of sarafloxacin in Atlantic Salmon, Salmo-Salar L. J. Fish Dis., 17: 111-121.
Matsumoto, S; Nakai, M; Yoshida, M and Katae, H (1998). Absorption, distribution and excretion of orbifloxacin in swines and calves. J. Japan Vet. Med. Assoc., 51: 13-18 (in Japanese).
Matsumoto, S; Takahashi, M; Yoshida, M; Komatsu, T; Kitadai, Y; Horii, Y and Katae, H (1997). Absorption, distribution and excretion of orbifloxacin in dogs and cats. J. Japan Vet. Med. Assoc., 50: 470-474 (in Japanese).
Munawar, SH; Iqbal, Z and Manzoor, Z (2017). Determination of renal handling of marbofloxacin in Lohi sheep (Ovis aries) following a single intravenous administration. Iran. J. Vet. Res., 18: 49-55.
Nakamura, S (1995). Veterinary use of new quinolones in Japan. Drugs. 49: 152-158.
Park, SC; Yun, HI and Oh, TK (1996). Comparative pharmacokinetics and tissue distribution of norfloxacin- glycine acetate in flounder, (Paralichthys olivaceus) at two different temperatures. J. Vet. Med. Sci., 58: 1039-1040. Paschoal, JAR; Quesada, SP; Goncalves, LU; Cyrino, JEP and Reyes, FGR (2013). Depletion study and estimation of the withdrawal period for enrofloxacin in pacu (Piaractus mesopotamicus). J. Vet. Pharmacol. Ther., 36: 594-602.
Tavakoli, M and Pourtaghi, H (2017). Molecular detection of virulence genes and multi-drug resistance patterns in Escherichia coli (STEC) in clinical bovine mastitis: Alborz province, Iran. Iran. J. Vet. Res., 18: 208-211.
Tynan, BE; Papich, MG; Kerl, ME and Cohn, LA (2016). Pharmacokinetics of minocycline in domestic cats. J. Feline. Med. Surg., 18: 257-263.
Vardali, SC; Kotzamanis, YP; Tyrpenou, AE and Samanidou, VF (2017). Danofloxacin depletion from muscle plus skin tissue of European sea bass (Dicentrarchus labrax) fed danofloxacin mesylate medicated feed in seawater at 16 degrees C and 27 degrees C. Aquaculture. 479: 538-543.
Watson, MK; Wittenburg, LA; Bui, CT; Jarosz, KA; Gustafson, DL and Johnston, MS (2015). Pharmacokinetics and bioavailability of orbifloxacin oral suspension in New Zealand White rabbits (Oryctolagus cuniculus). Am. J. Vet. Res., 76: 946-951.
Yang, F; Liu, YM; Li, ZL; Wang, YQ; Liu, BB; Zhao, ZS; Zhou, BH and Wang, GY (2017). Tissue distribution of marbofloxacin in pigs after a single intramuscular injection. J. Vet. Sci., 18: 169-173.
Yang, F; Sun, N; Liu, YM and Zeng, ZL (2015). Estimating danofloxacin withdrawal time in broiler chickens based on physiologically based pharmacokinetics modeling. J. Vet. Pharmacol. Ther., 38: 174-182.
Yang, F; Yang, YR; Wang, L; Huang, XH; Qiao, G and Zeng, ZL (2014). Estimating marbofloxacin withdrawal time in broiler chickens using a population physiologically based pharmacokinetics model. J. Vet. Pharmacol. Ther., 37: 579-588.
Yang, F; Yang, F; Wang, G; Shi, W; Kong, T; Yang, P; Bai, D and Zhou, B (2018). Pharmacokinetics of orbifloxacin in crucian carp (Carassius auratus) after intravenous and intramuscular administration. J. Vet. Pharmacol. Ther., 41: 599-604.
Zhu, YL; Tan, YP; Wang, CM; Zhang, N; Liu, YP; Liu, LN; Li, CM; Lu, XC and Cao, JY (2009). Pharmacokinetics and tissue residues of marbofloxacin in crucian carp (Carassius auratus) after oral administration. Aquac. Res., 40: 696-709. | ||
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