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Changes in broiler breeder hen’s immunity by zinc oxide and phytase | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 6، دوره 20، شماره 2 - شماره پیاپی 67، 2019، صفحه 120-125 اصل مقاله (377.16 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2019.5260 | ||
| نویسندگان | ||
| H. Sharideh1؛ M. Zhandi* 2؛ M. Zaghari2؛ A. Akhlaghi3؛ S. M. H. Hussaini1؛ A. R. Yousefi4 | ||
| 1Ph.D. Student in Animal Physiology, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran | ||
| 2Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran | ||
| 3Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran | ||
| 4Department of Research, Breeding and Production of Laboratory Animals, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran | ||
| چکیده | ||
| Background: The immune response of aged broiler breeder hens is influenced by many factors including obesity and aged lymphatic organs, but may improve by increasing the bioavailability of various nutrients such as zinc (Zn). Dietary supplementation of phytase can improve Zn availability in senescent broiler breeder hens. Aims: The aim of this study was to investigate the effect of supplementary zinc oxide (ZnO) and phytase in a maize-soybean meal-based diet on immune responses of broiler breeder hens. Methods: In a 2 × 4 factorial arrangement, a total of 128 hens were randomly assigned into eight groups. The birds received two levels of phytase (0 or 300 U/kg diet) and four levels of ZnO (30, 60, 90, and 120 mg/kg diet) for 13 successive wk (59-72 wk of age). Results: Results showed that phytase supplementation significantly increased immunoglobulin M (IgM), cutaneous basophil hypersensitivity (CBH) responses, total number of leukocytes, percentage of lymphocytes, and heterophil to lymphocyte ratios. The percentage of basophils and monocytes, however, decreased with phytase supplementation. Supplementation of ZnO increased anti-sheep red blood cells (SRBC) antibody titer, IgM, CBH responses, the total number of leukocytes, and the percentage of lymphocytes. Dietary supplementation of ZnO decreased the percentage of heterophil, and heterophil to lymphocyte ratio. A significant interaction effect of phytase and ZnO was found on the total number of leukocytes and percentage of lymphocytes. Conclusion: Dietary supplementation of ZnO (90 mg/kg diet) and phytase had some positive effects on improving immune responses in broiler breeder hens. | ||
| کلیدواژهها | ||
| Hen؛ Immunity؛ Leukocyte؛ Phytase؛ Zinc | ||
| مراجع | ||
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Akhlaghi, A; Zamiri, MJ; Jafari Ahangari, Y; Atashi, H; Ansari Pirsaraei, Z; Deldar, H; Eghbalian, A; Akhlaghi, A; Navidshad, B and Yussefi Kelarikolaei, K (2013). Oral exposure of broiler breeder hens to extra thyroxine modulates early adaptive immune responses in progeny chicks. Poult. Sci., 92: 1040-1049.
Brandao-Neto, J; De Mendonca, BB; Shuhama, T; Marchini, J; Pimenta, W and Tornero, M (1990). Zinc acutely and temporarily inhibits adrenal cortisol secretion in humans. Biol. Trace. Elem. Res., 24: 83-89.
Burton, R and Guion, CW (1968). The differential leucocyte blood count: its precision and individuality in the chicken. Poult. Sci., 47: 1945-1949.
Cowieson, AJ; Acamovic, T and Bedford, MR (2004). The effects of phytase and phytic acid on the loss of endogenous amino acids and minerals from broiler chickens. Br. Poult. Sci., 45: 101-108.
Cowieson, AJ and Ravindran, V (2007). Effect of phytic acid and microbial phytase on the flow and amino acid composition of endogenous protein at the terminal ileum of growing broiler chickens. Br. J. Nutr., 98: 745-752.
Dardenne, M and Bach, JM (1993). Rationale for the mechanism of zinc interaction in the immune system. 1st Edn., Marcel Dekker Inc., New York, CRC Press, PP: 501-509.
Feng, J; Ma, WQ; Niu, HH; Wu, X and Wang, Y (2010). Effects of zinc glycine chelate on growth, hematological, and immunological characteristics in broilers. Biol. Trace. Elem. Res., 133: 203-211.
Gross, WB and Siegel, HS (1983). Evaluation of the heterophil/lymphocyte ratio as a measure of stress in chickens. Avian Dis., 27: 972-979.
Hudson, BP; Dozier Iii, WA; Wilson, JL; Sander, J and Ward, T (2004). Reproductive performance and immune status of caged broiler breeder hens provided diets supplemented with either inorganic or organic sources of zinc from hatching to 65 wk of age. J. Appl. Poult. Res., 13: 349-359.
Imboden, JB; Weiss, A and Stobo, JD (1985). The antigen receptor on a human T cell line initiates activation by increasing cytoplasmic free calcium. J. Immunol., 134: 663-665.
Kidd, MT (2004). Nutritional modulation of immune function in broilers. Poult. Sci., 83: 650-657.
Kidd, MT; Ferket, PR and Qureshi, MA (1996). Zinc metabolism with special reference to its role in immunity. Worlds Poult. Sci. J., 52: 309-324.
Liu, BL; Rafiq, A; Tzeng, YM and Rob, A (1998). The induction and characterization of phytase and beyond. Enzyme. Microb. Technol., 22: 415-424.
Liu, N; Ru, YJ; Cowieson, AJ; Li, F and Cheng, XC (2008). Effects of phytate and phytase on the performance and immune function of broilers fed nutritionally marginal diets. Poult. Sci., 87: 1105-1111.
Maenz, DD (2001). Enzymatic characteristics of phytases as they relate to their use in animal feeds. In: Bedfords, MR (Ed.), Enzymes in farm animal nutrition. (2nd Edn.), Wallingford, UK, CABI Publishing, CAB International. PP: 61-84.
Maenz, DD and Classen, HL (1998). Phytase activity in the small intestinal brush border membrane of the chicken. Poult. Sci., 77: 557-563.
McDowell, LR (1992). Minerals in animal and human nutrition. 2nd Edn., Gainesville, Florida, USA, Academic Press Inc., PP: 357-395.
Menniti, FS; Oliver, KG; Putney Jr, JW and Shears, SB (1993). Inositol phosphates and cell signaling: new views of InsP5 and InsP6. Trends Biochem. Sci., 18: 53-56.
Prasad, AS (1993). Acquired zinc deficiency and immune dysfunction in sickle cell anemia. 1st Edn., Marcel Dekker, New York, CRC Press. PP: 393-409.
Sebastian, S; Touchburn, SP; Chavez, ER and Lague, PC (1996). The effects of supplemental microbial phytase on the performance and utilization of dietary calcium, phosphorus, copper, and zinc in broiler chickens fed corn-soybean diets. Poult. Sci., 75: 729-736.
Shamsuddin, AM (2002). Anti-cancer function of phytic acid. Int. J. food Sci. Technol., 37: 769-782.
Sharideh, H and Zaghari, M (2017). Effect of light emitting diodes with different color temperatures on immune responses and growth performance of male broiler. Ann. Anim. Sci., 17: 545-553.
Shears, SB (1996). Inositol pentakis-and hexakisphosphate metabolism adds versatility to the actions of inositol polyphosphates novel effects on ion channels and protein traffic. In: Biswas, BB and Biswas, S (Eds.), Myo-inositol phosphates, phosphoinositides, and signal transduction. Vol., 26, Boston, MA, Springer. PP: 187-226. Smith, MO (2003). Effects of different levels of zinc on the performance and immunocompetence of broilers under heat stress. Poult. Sci., 82: 1580-1588.
Sunder, GS; Panda, AK; Gopinath, NCS; Rao, SR; Raju, M; Reddy, M and Kumar, CV (2008). Effects of higher levels of zinc supplementation on performance, mineral availability, and immune competence in broiler chickens. J. Appl. Poult. Res., 17: 79-86.
Torroba, M and Zapata, AG (2003). Aging of the vertebrate immune system. Microsc. Res. Tech., 62: 477-481.
Underwood, EJ (1977). Trace elements in human and animal nutrition. 4th Edn., New York, Academic Press. PP: 1-499.
Van der Zijpp, AJ and Leenstra, FR (1980). Genetic analysis of the humoral immune response of white leghorn chicks. Poult. Sci., 59: 1363-1369.
Vruwink, KG; Keen, CL; Gershwin, ME; Mareschi, JP and Hurley, LS (1993). The effect of experimental zinc deficiency on development of the immune system. 1st Edn., Marcel Dekker, New York, CRC Press. PP: 263-279.
Wellinghausen, N and Rink, L (1998). The significance of zinc for leukocyte biology. J. Leukoc. Biol., 64: 571-577.
Wu, B; Li, L; Ruan, T and Peng, X (2018). Effect of methionine deficiency on duodenal and jejunal IgA+ B cell count and immunoglobulin level of broilers. Iran. J. Vet. Res., 19: 165-171.
Zyla, K; Wikiera, A; Koreleski, J; Swiatkiewicz, S; Piironen, J and Ledoux, D (2000). Comparison of the efficacies of a novel Aspergillus niger mycelium with separate and combined effectiveness of phytase, acid phosphatase, and pectinase in dephosphorylation of wheat-based feeds fed to growing broilers. Poult. Sci., 79: 1434-1443. | ||
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