| تعداد نشریات | 24 |
| تعداد شماره‌ها | 934 |
| تعداد مقالات | 8,383 |
| تعداد مشاهده مقاله | 16,981,303 |
| تعداد دریافت فایل اصل مقاله | 14,371,047 |
Clinical studies on progressive retinal atrophy in 31 dogs | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 8، دوره 18، شماره 2 - شماره پیاپی 59، 2017، صفحه 119-123 اصل مقاله (376.66 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2017.4096 | ||
| نویسندگان | ||
| D. N. Kelawala1؛ D. B. Patil* 2؛ P. V. Parikh2؛ M. J. Sheth3؛ C. G. Joshi4؛ B. Reddy4 | ||
| 1Ph.D. Scholar in Veterinary Surgery and Radiology, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand, Gujarat-388001, India | ||
| 2Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand, Gujarat-388001, India | ||
| 3Consultant Vitreoretinal Surgeon, Govind Eye Clinic, Vadodara, India | ||
| 4Department of Animal Biotechnology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University, Anand, Gujarat-388001, India | ||
| چکیده | ||
| During a 2-year period, 31 cases of a hereditary retinal degeneration in dogs bred in India were found mainly suspected for progressive retinal atrophy (PRA) with typical history of initial nyctalopia followed by hemeralopia. Out of 31 PRA suspected dogs, 8 dogs (26%) were from the age group of 1-5 years, 15 (48%) 6-10 years and the rest (26%) 11-15 years. The most predominant breed was Spitz (18 dogs, 58%). Detailed ophthalmologic examinations included Schirmer’s tear test, fluorescein stain, applanation tonometry, slit lamp biomicroscopy and ocular ultrasound in appropriate cases. Ophthalmoscopic and fundoscopic changes included hyperreflectivity and discoloration of the tapetal area, marked attenuation of retinal vessels, depigmentation in non-tapetal area and optic disc atrophy with scalloped borders. Electroretinograms (ERG) recorded in 13 PRA-affected cases revealed non-recordable extinguished (flatline) ERG responses. A reduction mainly of a- and b-wave amplitudes in the ERG indicated a generalized photoreceptor disease. | ||
| کلیدواژه‌ها | ||
| dog؛ Electroretinography؛ Funduscopy؛ Progressive retinal atrophy | ||
| مراجع | ||
|
Bedford, P (2006). Hereditary retinal diseases. World Con-gress WSAVA/FECAVA/CSAVA. PP: 609-610.
Clements, PJM; Sargan, DR; Gould, DJ and Petersen-Jones, SM (1996). Recent advances in understanding the spectrum of canine generalised progressive retinal atrophy. J. Small Ani. Prac., 37: 155-162.
Cooper, AE; Ahonen, S; Rowlan, JS; Duncan, A; Seppala, EH; Vanhapelto, P; Lohi, H and Komaromy, AM (2014). A novel form of progressive retinal atrophy in Swedish Vallhund dogs. PLoS One. 9: 1-10.
Downs, LM; Wallin-Hakansson, B; Boursnell, M; Marklund, S; Hedhammar, Å; Truvé, K; Hübinette, L; Lindblad-Toh, K; Bergström, T and Mellersh, CS (2011). A frameshift mutation in golden retriever dogs with progressive retinal atrophy endorses SLC4A3 as a candidate gene for human retinal degenerations. PLoS One. 6: e21452. Gomes, D; Otsuki, DA; Lisaki, R; Angélica De Mendonçaand Safatle, V (2013). Generalized progressive retinal atrophy in Cocker Spaniel dogs. Cienc. Rural. 43: 1405-1414.
Haim, M; Holm, NV and Rosenberg, T (1992). Prevalence of retinitis pigmentosa and allied disorders in Denmark. I Main results. Acta Ophthalmol., 70: 178-186.
Jeong, MB; Shin, AP; Kim, SE; Park, YW; Narfström, K and Seo, K (2013). Clinical and electroretinographic findings of progressive retinal atrophy in miniature Schnauzer dogs of South Korea. J. Vet. Med. Sci., 75: 1303-1308.
Kelawala, DN (2014). Studies on electroretinography using RETIport ERG system in canines. M.V.Sc. thesis sub-mitted to AnandAgriculturalUniversity, Anand, Gujarat-388110, India. P: 68.
Maggs, DJ (2013). Basic diagnostic techniques. In: Maggs, DJ; Miller, P and Ofri, R (Eds.), Slatter’s fundamentals of veterinary ophthalmology. (5th Edn.), Philadelphia, Saunders. PP: 1-12.
Millichamp, J (1990). Retinal degeneration in the dog and cat. Vet. Clinics North America: Small Ani. Prac., 20: 799-835.
Miyadera, K; Acland, GM and Aguirre, GD (2012a). Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm. Genome. 23: 40-61.
Miyadera, K; Kato, K; Boursnell, M; Mellersh, CS and Sargan, DR (2012b). Genome-wide association study in RPGRIP-/-dogs identifies a modifier locus that determines the onset of retinal degeneration. Mamm. Genome. 23: 212-223.
Narfström, K; Ekesten, B; Rosolen, SG; Spiess, BM; Percicot, CL and Ofri, R (2002). Guidelines for clinical electroretinography in the dog. Doc. Ophthalmol., 105: 83-92.
Narfstrom, K; Galle, L; Dubielzig, R and Katz, M (2006). Screening for late on-set progressive retinal atrophy in the English springer spaniel dog using a portable ERG unit and an automated protocol. International Society for Clinical Electrophysiology of Vision (ISCEV), 44th Annual Sym-posium, Fontevraud Abbey, France, Abstract S2-20, June, 2006.
Narfstrom, K and Petersen-Jones, S (2013). Diseases of the canine ocular fundus. In: Gelatt, KN; Gilger, BC and Kern, TJ (Eds.), Veterinary ophthalmology. (5th Edn.), Ames, Wiley-Blackwell. PP: 1303-1392.
Petersen-Jones, SM (1998). A review of research to elucidate the causes of the generalized progressive retinal atrophies. Vet. J., 155: 5-18.
Reddy, B; Kelawala, DN; Shah, T; Patel, AB; Patil, DB; Parikh, PV; Patel, N; Parmar, N; Mohapatra, AB; Singh, KM; Menon, R; Pandya, D; Jakhesara, SJ; Koringa, PG; Rao, MV and JOSHI, CG (2015).Identification of putative SNPs in progressive retinal atrophy affected Canis lupus familiaris using exome sequencing. Mamm. Genome. 26: 638-649.
Svensson, M; Olsen, L; Winkler, PA; Petersen-Jones, SM; Bergstrom, T; Garncarz, Y and Narfstrom, K (2015). Progressive retinal atrophy in the Polski Owczarek Nizinny dog: a clinical and genetic study. Vet. Ophthalmol., 19: 195-205. | ||
|
آمار تعداد مشاهده مقاله: 1,211 تعداد دریافت فایل اصل مقاله: 1,135 |
||