| تعداد نشریات | 24 |
| تعداد شمارهها | 917 |
| تعداد مقالات | 8,230 |
| تعداد مشاهده مقاله | 16,274,686 |
| تعداد دریافت فایل اصل مقاله | 13,751,814 |
Efficacy of thermostable I-2 Newcastle disease vaccine compared to B1 commercial vaccine in broiler chicken | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 5، دوره 18، شماره 2 - شماره پیاپی 59، 2017، صفحه 103-107 اصل مقاله (264.47 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2017.4089 | ||
| نویسندگان | ||
| A. H. Asl Najjari1؛ H. Nili* 2؛ K. Asasi3؛ N. Mosleh3؛ H. Rohollahzadeh1؛ S. Mokhayeri1 | ||
| 1Resident of Diseases of Poultry, Avian Diseases Research Center, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
| 2Avian Diseases Research Center, School of Veterinary Medicine, Shiraz University, Shiraz, Iran; 3Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran | ||
| 3Avian Diseases Research Center, School of Veterinary Medicine, Shiraz University, Shiraz, Iran; Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran | ||
| چکیده | ||
| Frequent vaccination failures have occurred in the broiler farms in Eurasian countries during Newcastle disease outbreaks. The disease is enzootic in many countries of the region, especially in southwest Asia. I-2 vaccine has been used successfully in village chickens in many Asian and African countries. Our preliminary study showed good efficacy of the vaccine in broiler chickens. Therefore the current experimental study was conducted to compare viral shedding period of heat resistance I-2 vaccine with B1 commercial vaccine following challenge with Herts’33. For this purpose three hundred commercial broilers were randomly allocated into four groups; 1) Thermostable I-2 vaccine, 2) Hitchner B1 vaccine, 3) Challenge group with no vaccine, and 4) Negative control group. Experimental chicks were vaccinated on days 19 and 26 by the eye drop route and then the birds were challenged via intra ocular route on day 40 with a suspension containing 106 EID50/ml challenge virus. Experimental chickens were monitored by collecting buccal and cloacal swabs at different times. Collected swabs were submitted to PCR test. The results showed that vaccination can protect the birds against mortality and also decrease virus shedding; also there was not a significant difference between vaccination with I-2 and B1 vaccines. | ||
| کلیدواژهها | ||
| Broiler chicken؛ Hitchner B1 vaccine؛ Newcastle disease؛ Thermostable I-2 vaccine؛ Virus Shedding | ||
| مراجع | ||
|
Alexander, DJ (2000). Newcastle disease and other avian paramyxoviruses. Rev. Sci. Tech. Oie., 19: 443-455.
Alexander, DJ; Bell, JG and Alders, RG (2004). A technology review: Newcastle disease, with special emphasis on its effect on village chickens (No. 161). Food & Agriculture Org.
Alexander, DJ and Senne, D (2008). Newcastle disease and other avian paramyxoviruses. In: Dufour-Zavala, L (Ed.), A laboratory manual for the isolation, identification and characterization of avian pathogens. (5th Edn.), Athens, GA, American Association of Avian Pathologists. PP: 135-141.
Degefa, T; Dadi, L; Yami, A and Nassir, M (2004). Technical and economic evaluation of different methods of Newcastle disease vaccine administration. J. Vet. Med. A., 51: 365-369.
Fentie, T; Dadi, K; Kassa, T; Sahle, M and Cattoli, G (2014). Effect of vaccination on transmission characte-ristics of highly virulent Newcastle disease virus in experimentally infected chickens. Avian Pathol., 43: 420-426.
Firouzi, S; Nili, H; Asasi, K; Nazifi, S; Mosleh, N; Habibi, H and Mohammadi, M (2014). Acute phase responses in commercial broiler chickens experimentally infected with a highly virulent Newcastle disease virus strain. OJVR., 18: 495-502.
Habibi, H; Nili, H; Asasi, K; Mosleh, N; Firouzi, S and Mohammadi, M (2015). Efficacy and transmissibility of Newcastle disease I-2 vaccine strain against a field isolate of virulent Nd virus (Jf820294.1) in village chicken. Trop. Anim. Health Pro., 47: 73-78.
Kant, A; Koch, G; Van Roozelaar, D; Balk, F and Huurne, AT (1997). Differentiation of virulent and non-virulent strains of Newcastle disease virus within 24 hours by polymerase chain reaction. Avian Pathol., 26: 837-849.
Kapczynski, DR and King, DJ (2005). Protection of chickens against overt clinical disease and determination of viral shedding following vaccination with commercially available Newcastle disease virus vaccines upon challenge with highly virulent virus from the California 2002 exotic Newcastle disease outbreak. Vaccine. 23: 3424-3433.
Mayo, M (2002). A summary of taxonomic changes recently approved by Ictv. Arch. Virol., 147: 1655-1656.
Miller, PJ; Estevez, C; Yu, Q; Suarez, DL and King, DJ (2009). Comparison of viral shedding following vacci-nation with inactivated and live Newcastle disease vaccines formulated with wild-type and recombinant viruses. Avian Dis., 53: 39-49. Nasser, M; Lohr, J; Mebratu, G; Zessin, KH; Baumann, M and Ademe, Z (2000). Oral Newcastle disease vaccination trials in ethiopia. Avian Pathol., 29: 27-34.
Van Boven, M; Bouma, A; Fabri, TH; Katsma, E; Hartog, L and Koch, G (2008). Herd immunity to Newcastle disease virus in poultry by vaccination. Avian Pathol., 37: 1-5.
Villegas, P and Purchase, HG (1998). Titration of biological suspensions. In: Swayne, DE; Glisson, JR; Jackwood, MW; Pearson, JE and Reed, WM (Eds.), A laboratory manual for the isolation and identification of avian pathogens. (4th Edn.), Kennett Square, PA, American Association of Avian Pathologists. PP: 248-253.
Wambura, P (2009). Oral vaccination of chickens against Newcastle disease with I-2 vaccine coated on oiled rice. Trop. Anim. Health Pro., 41: 205-208.
Young, M; Alders, R; Grimes, S; Spradbrow, PB; Dias, P; da Silva, A and Lobo, Q (2002). Controlling Newcastle disease in village chickens: A laboratory manual. ACIAR Monographs No. 87. PP: 52-85. | ||
|
آمار تعداد مشاهده مقاله: 2,569 تعداد دریافت فایل اصل مقاله: 1,125 |
||