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Association of VNTR polymorphism of tumor necrosis factor receptor 2 (TNFRSF1B) with pulmonary tuberculosis | ||
| Molecular Biology Research Communications | ||
| مقاله 3، دوره 6، شماره 1، 2017، صفحه 23-26 اصل مقاله (67.6 K) | ||
| نوع مقاله: Short communication | ||
| شناسه دیجیتال (DOI): 10.22099/mbrc.2017.3939 | ||
| نویسندگان | ||
| Mohammad Naderi1؛ Mohammad Hashemi* 2؛ Nazanin Moradi2 | ||
| 1Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran | ||
| 2Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran | ||
| چکیده | ||
| This study was designed to find out the impact of the variable number of tandem repeats (VNTR) of the tumor necrosis factor receptor 2 (TNFRSF1B) on pulmonary tuberculosis (PTB) risk in an Iranian population. This case-control study was done on 159 PTB patients and 158 healthy subjects. Bi-allelic TNFRSF1B VNTR was genotyped by polymerase chain reaction. Logistic regression analysis revealed no significant association between TNFRSF1B VNTR and PTB risk (P>0.05). Our findings proposed that TNFRSF1B VNTR polymorphism is unlikely to confer susceptibility to PTB. | ||
| کلیدواژهها | ||
| Pulmonary tuberculosis؛ TNFRSF1B؛ VNTR؛ Polymorphism | ||
| مراجع | ||
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1. WHO. WHO Global tuberculosis report 2016. Available at: http://apps.who.int/iris/ bitstream/10665/250441/1/9789241565394-eng.pdf?ua=1. 2016. 2. Zumla A, George A, Sharma V, Herbert N, Baroness Masham of I. WHO's 2013 global report on tuberculosis: successes, threats, and opportunities. Lancet 2013;382: 1765-1767. 3. Azad AK, Sadee W, Schlesinger LS. Innate immune gene polymorphisms in tuberculosis. Infect Immun 2012;80:3343-3359. 4. Naderi M, Hashemi M, Safdari A, Bahari G, Taheri M. Association of genetic polymorphisms of CISH with the risk of pulmonary tuberculosis in Zahedan, southeast Iran. Braz J Infect Dis 2016;20:379-383. 5. Naderi M, Hashemi M, Amininia S. Association of TAP1 and TAP2 gene polymorphisms with susceptibility to pulmonary tuberculosis. Iran J Allergy Asthma Immunol 2016;15:62-68. 6. Hashemi M, Sharifi-Mood B, Rasouli A, Amininia S, Naderi M, Taheri M. Macrophage migration inhibitory factor -173 G/C polymorphism is associated with an increased risk of pulmonary tuberculosis in Zaheda, southeast Iran. EXCLI J 2015;14:117-122. 7. Satoh H, Firestein GS, Billings PB, Harris JP, Keithley EM. Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope 2002;112:1627-1634. 8. Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol 1999;17:331-367. 9. Mokrousov I, Wu XR, Vyazovaya A, Feng WX, Sun L, Xiao J, Miao Q, Jiao WW, Shen A. Polymorphism of 3'UTR region of TNFR2 coding gene and its role in clinical tuberculosis in Han Chinese pediatric population. Infect Genet Evol 2011;11: 1312-1318. 10. Abebe M, Doherty TM, Wassie L, Aseffa A, Bobosha K, Demissie A, Zewdie M, Engers H, Andersen P, Kim L, Huggett J, Rook G, Yamuah LK, Zumla A, group Vs. Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status. Eur J Immunol 2010;40:291-301. 11. Moller M, Flachsbart F, Till A, Thye T, Horstmann RD, Meyer CG, Osei I, van Helden PD, Hoal EG, Schreiber S, Nebel A, Franke A. A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations. Am J Respir Crit Care Med 2010;181:388-393. 12. Naderi M, Hashemi M, Taheri M, Pesarakli H, Eskandari-Nasab E, Bahari G. CD209 promoter -336 A/G (rs4804803) polymorphism is associated with susceptibility to pulmonary tuberculosis in Zahedan, southeast Iran. J Microbiol Immunol Infect 2014;47:171-175. 13. Sainz J, Perez E, Hassan L, Moratalla A, Romero A, Collado MD, Jurado M. Variable number of tandem repeats of TNF receptor type 2 promoter as genetic biomarker of susceptibility to develop invasive pulmonary aspergillosis. Hum Immunol 2007;68:41-50. 14. Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996;334:1717-1725. 15. Steinshamn S, Bemelmans MH, van Tits LJ, Bergh K, Buurman WA, Waage A. TNF receptors in murine Candida albicans infection: evidence for an important role of TNF receptor p55 in antifungal defense. J Immunol 1996;157:2155-2159. 16. Chavez-Galan L, Vesin D, Segueni N, Prasad P, Buser-Llinares R, Blaser G, Pache JC, Ryffel B, Quesniaux VF, Garcia I. Tumor necrosis factor and its receptors are crucial to control Mycobacterium bovis Bacillus Calmette-Guerin pleural infection in a murine model. Am J Pathol 2016;186:2364-2377. 17. Santee SM, Owen-Schaub LB. Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization. J Biol Chem 1996;271: 21151-21159. 18. Vandenabeele P, Declercq W, Vercammen D, Van de Craen M, Grooten J, Loetscher H, Brockhaus M, Lesslauer W, Fiers W. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma. J Exp Med 1992;176:1015-1024. 19. Grell M, Douni E, Wajant H, Lohden M, Clauss M, Maxeiner B, Georgopoulos S, Lesslauer W, Kollias G, Pfizenmaier K, Scheurich P. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995;83:793-802. | ||
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