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Association of VNTR polymorphism of tumor necrosis factor receptor 2 (TNFRSF1B) with pulmonary tuberculosis | ||
| Molecular Biology Research Communications | ||
| مقاله 3، دوره 6، شماره 1، 2017، صفحه 23-26 اصل مقاله (67.6 K) | ||
| نوع مقاله: Short communication | ||
| شناسه دیجیتال (DOI): 10.22099/mbrc.2017.3939 | ||
| نویسندگان | ||
| Mohammad Naderi1؛ Mohammad Hashemi* 2؛ Nazanin Moradi2 | ||
| 1Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran | ||
| 2Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran | ||
| چکیده | ||
| This study was designed to find out the impact of the variable number of tandem repeats (VNTR) of the tumor necrosis factor receptor 2 (TNFRSF1B) on pulmonary tuberculosis (PTB) risk in an Iranian population. This case-control study was done on 159 PTB patients and 158 healthy subjects. Bi-allelic TNFRSF1B VNTR was genotyped by polymerase chain reaction. Logistic regression analysis revealed no significant association between TNFRSF1B VNTR and PTB risk (P>0.05). Our findings proposed that TNFRSF1B VNTR polymorphism is unlikely to confer susceptibility to PTB. | ||
| کلیدواژهها | ||
| Pulmonary tuberculosis؛ TNFRSF1B؛ VNTR؛ Polymorphism | ||
| مراجع | ||
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