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Administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) for the intracranial hemorrhage in two dogs: a case report | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 13، دوره 17، شماره 1 - شماره پیاپی 54، 2016، صفحه 62-65 اصل مقاله (259.55 K) | ||
| نوع مقاله: Scientific report | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2016.3607 | ||
| نویسندگان | ||
| M.H. Kang؛ H.M. Park* | ||
| Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 143-701, South Korea | ||
| چکیده | ||
| Two dogs with generalized seizures were evaluated. The dogs were diagnosed with traumatic intracranial hemorrhages based on the history, neurological examinations, and magnetic resonance imaging (MRI) of the brain. Treatment was started with oxygen, prednisolone and anticonvulsant agents. No further seizure activity was observed after treatment in both dogs, however cushing reflex was detected in case 1 and a left-sided hemi-paresis was detected in case 2. Further supportive treatment with recombinant human granulocyte colony-stimulating factor (rhG-CSF) was attempted. No abnormal signs were noted in either of the dogs and no recurrence was noted 16 and 14 months later, in case 1 and 2, respectively. These cases indicate that a combination of rhG-CSF treatment with previous therapy could be used in dogs with traumatic brain injury. | ||
| کلیدواژهها | ||
| Granulocyte colony-stimulating factor؛ Intracranial hemorrhage؛ Magnetic resonance imaging؛ Traumatic brain injury | ||
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