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SCREENING AND POTENTIAL OF MULTI-DRUG RESISTANCE IN GRAM NEGATIVE BACTERIA FROM HOSPITAL WASTEWATER | ||
| Iranian Journal of Science | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 28 بهمن 1394 | ||
| نوع مقاله: Research Note | ||
| شناسه دیجیتال (DOI): 10.22099/ijsts.2016.3591 | ||
| نویسندگان | ||
| Manzar Alam1؛ Mohd Imran* 2 | ||
| 1Deparment of Biosceinces, Integral University, Lucknow | ||
| 2Department of Biosceinces, Integral University | ||
| چکیده | ||
| The antibiotic resistance profiles of Gram negative bacterial isolated from four different sampling sites of the hospital wastewater at Lucknow city was evaluated. Of the 200 Gram negative bacterial isolates tested, marked antibiotic resistances (over 90%) were observed for amoxicillin, methicillin, ampicillin, nalidixic acid and penicillin depending upon the sampling sites. All Gram negative bacterial isolates also showed multiple resistance patterns (2-13 antibiotics) in different combination of antibiotics. The MAR index ranges were found (0.01-0.86) indicating the high risk of environmental contamination. The findings indicated that pollution of aquatic environments from different sources of the city may have a significant contribution on the emergence and dissemination of resistance in Gram negative bacteria as well as other pathogenic bacteria in the hospital wastewater. This over use of antibiotics as well as other pharmaceuticals in the hospital and their introduction into the aquatic environment may have a potential public health risk. | ||
| کلیدواژهها | ||
| Hospital wastewater؛ Gram negative bacteria؛ antibiotic susceptibility؛ multiple-drug resistance (M.D.R)؛ multiple antibiotic resistance index (M.A.R) | ||
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آمار تعداد مشاهده مقاله: 946 |
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