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Hadi, Z., Atashi, H., Dadpasand, M., Derakhshandeh, A., Ghahramani Seno, M. M.. (1394). The relationship between growth hormone polymorphism and growth hormone receptor genes with milk yield and reproductive performance in Holstein dairy cows. , 16(3), 244-248. doi: 10.22099/ijvr.2015.3188
Z. Hadi; H. Atashi; M. Dadpasand; A. Derakhshandeh; M. M. Ghahramani Seno. "The relationship between growth hormone polymorphism and growth hormone receptor genes with milk yield and reproductive performance in Holstein dairy cows". , 16, 3, 1394, 244-248. doi: 10.22099/ijvr.2015.3188
Hadi, Z., Atashi, H., Dadpasand, M., Derakhshandeh, A., Ghahramani Seno, M. M.. (1394). 'The relationship between growth hormone polymorphism and growth hormone receptor genes with milk yield and reproductive performance in Holstein dairy cows', , 16(3), pp. 244-248. doi: 10.22099/ijvr.2015.3188
Hadi, Z., Atashi, H., Dadpasand, M., Derakhshandeh, A., Ghahramani Seno, M. M.. The relationship between growth hormone polymorphism and growth hormone receptor genes with milk yield and reproductive performance in Holstein dairy cows. , 1394; 16(3): 244-248. doi: 10.22099/ijvr.2015.3188

The relationship between growth hormone polymorphism and growth hormone receptor genes with milk yield and reproductive performance in Holstein dairy cows

Iranian Journal of Veterinary Research
مقاله 1، دوره 16، شماره 3 - شماره پیاپی 52، 2015، صفحه 244-248    اصل مقاله (238.57 K)
نوع مقاله: Full paper (Original article)
شناسه دیجیتال (DOI): 10.22099/ijvr.2015.3188
نویسندگان
Z. Hadi1؛ H. Atashi* 1؛ M. Dadpasand1؛ A. Derakhshandeh2؛ M. M. Ghahramani Seno3
1Department of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran
2Department of Pathobiology, School of Veterinary Science, Shiraz University, Shiraz, Iran
3Department of Basic Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
چکیده
The aim of this study was to investigate the potential association between growth hormone GH/AluI and growth hormone receptor GHR/AluI polymorphisms with milk yield and reproductive performances in Holstein dairy cows in Iran. Blood samples of 150 Holstein cows were collected and their genomic DNA was extracted using Gene-Fanavaran DNA extracting kit. Fragments of the 428 bp of exon 5 growth hormone (GH) gene and the 342 bp of exon 10 growth hormone receptor (GHR) gene were amplified using the polymerase chain reaction (PCR) method. PCR products were digested by the AluI restriction enzyme and electrophoresed
on 3% agarose gel. Continuous and categorical data were analyzed using linear mixed models through Proc MIXED and logistic regression models through Proc GENMOD of SAS software, respectively. The results showed no relationship between the examined traits and GH/AluI or GHR/AluI genes. A significant relationship was found between GH/AluI polymorphism and dystocia, but the presence of the GH-L allele reduced the incidence of dystocia. The results suggest that the GH-LL genotype reduces dystocia
probably by affecting the release of growth hormone; nevertheless, further studies will be needed to examine the relationship between dystocia and GH genotypes.
کلیدواژه‌ها
Dystocia؛ Logistic regression؛ Stillbirth
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