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Jabbari, A. R., Moazeni Jula, G. R.. (1385). Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test. , 8(1), 83-85. doi: 10.22099/ijvr.2007.2713
A. R. Jabbari; G. R. Moazeni Jula. "Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test". , 8, 1, 1385, 83-85. doi: 10.22099/ijvr.2007.2713
Jabbari, A. R., Moazeni Jula, G. R.. (1385). 'Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test', , 8(1), pp. 83-85. doi: 10.22099/ijvr.2007.2713
Jabbari, A. R., Moazeni Jula, G. R.. Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test. , 1385; 8(1): 83-85. doi: 10.22099/ijvr.2007.2713

Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test

Iranian Journal of Veterinary Research
مقاله 13، دوره 8، شماره 1 - شماره پیاپی 18، 2007، صفحه 83-85    اصل مقاله (20.76 K)
نوع مقاله: Short paper
شناسه دیجیتال (DOI): 10.22099/ijvr.2007.2713
نویسندگان
A. R. Jabbari* ؛ G. R. Moazeni Jula
Department of Aerobic Veterinary Bacterial Vaccine, Razi Vaccine and Serum Research Institute, Karadj, Iran
چکیده
Haemorrhagic septicaemia (HS) vaccine which is prepared in Razi Institute is used in endemic areas of
Iran. Aluminum-hydroxide gel was used as adjuvant for preparing this vaccine. Post-vaccinal shock reactions
were the main complaint after use of this vaccine. In a previous study, we could improve the vaccine by
alum-precipitation Pasteurella multocida cells and removing the liquid phase. In this study, the amount of
free endotoxin in aluminum-hydroxide and alum-HS vaccines was determined. It was found that endotoxin
level was considerably decreased from 0.22 EU/ml to 0.03 EU/ml after alum-precipitation.
کلیدواژه‌ها
Haemorrhagic septicaemia vaccine؛ Endotoxin؛ Shock reaction؛ LAL test
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