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The effect of ubiquinone on functional recovery and morphometric indices of sciatic nerve regeneration | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 14، دوره 15، شماره 4 - شماره پیاپی 49، 2014، صفحه 392-396 اصل مقاله (224.04 K) | ||
| نوع مقاله: Full paper (Original article) | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2014.2598 | ||
| نویسندگان | ||
| Z. Moradi1؛ S. Azizi* 2؛ R. Hobbenaghi3 | ||
| 1Graduated from Faculty of Veterinary Medicine, Urmia University, Urmia, Iran | ||
| 2Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran | ||
| 3Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran | ||
| چکیده | ||
| A common cause of peripheral nerve injury is trauma. The positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. In this experiment, the effect of intraperitoneal administration of ubiquinone (CoQ10) on an acute experimentally sciatic nerve crush was studied in a rat model. Forty-five male Wistar rats, weighing between 160-180 g were used. The rats were randomly divided into two experimental groups (n=20). Each group was further subdivided into four subgroups of five animals each. Functional studies confirmed the faster recovery of regenerated axons in the treatment group compared to the un-treated group (P | ||
| کلیدواژهها | ||
| Ubiquinone (coenzyme Q10)؛ Peripheral nerve regeneration؛ Crush | ||
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