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Association between bovine lactoferrin gene variant and somatic cell count in milk based on EcoRI restriction site | ||
| Iranian Journal of Veterinary Research | ||
| مقاله 13، دوره 15، شماره 1 - شماره پیاپی 46، 2014، صفحه 62-65 اصل مقاله (139.79 K) | ||
| نوع مقاله: Short paper | ||
| شناسه دیجیتال (DOI): 10.22099/ijvr.2014.1985 | ||
| نویسندگان | ||
| V. Hemati Doust؛ G. Rahimi-Mianji؛ A. Farhadi* | ||
| Laboratory for Molecular Genetics and Animal Biotechnology, Faculty of Animal Science and Fisheries, Sari Agricultural Sciences and Natural Resources University, Sari, Iran | ||
| چکیده | ||
| Mastitis is one of the most serious and costly diseases affecting dairy cattle production. In the present study, effects of a lactoferrin gene polymorphism (intron 6) on milk somatic cell count (SCC) and subclinical mastitis was investigated in 121 Holstein dairy cattle. Two alleles of A and B and two genotypes of AA and AB were found in an EcoRI recognized single nucleotide polymorphism in intron 6 of lactoferin gene with the frequencies of 85.12, 14.88, 70.25 and 29.75%, respectively. No homozygous BB cows were detected in the studied population. Marker-traits association analysis showed that EcoRI marker site in lactoferrin gene was significantly related to SCC (P≤0.01) with AB as a desirable genotype. The obtained results in the present study indicated that selection of the AB genotypes for EcoRI recognized single nucleotide polymorphism might contribute to a reduction of SCC in Holstein dairy cattle. | ||
| کلیدواژهها | ||
| Lactoferrin؛ Somatic cell count؛ Polymorphism | ||
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