1Department of Pathology, Faculty of Specialized Veterinary Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran
2Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran
3DMV Student, Faculty of Specialized Veterinary Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran
چکیده
This is a report of a penile fibrosarcoma in a two-year-old crossbred Holstein bull. The ulcerated tumor mass with dimensions of 7 × 9 × 6.5 cm, was enveloped the glans and body of the penis. It had a white-gray color at cross section appearance. There was no metastatic evidence of regional lymph node enlargement. Histopathologically, elongated spindle-shaped cells arranged densely in the interwoven pattern had a low rate of mitosis with oddly-shaped nuclei and pleomorphism. Immunohistochemically, the neoplastic cells were positive for vimentin and S100, but negative for α-smooth muscle actin, desmin, C-KIT and GFAP.